CD38 antibody (Biotin)

Catalog No. ABIN303555

Product Details anti-CD38 Antibody (Biotin)

Target: CD38

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD38 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Specificity: This antibody reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes, it is an antigenic marker of lymphoid cells.

Cross-Reactivity (Details): Species reactivity (tested):Human

Immunogen: Human thymocytes in foetus

Clone: HIT2

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry analysis: 1:500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD38

Target: CD38

Abstract: CD38 Products

Background: CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1

Gene ID: 952

UniProt: P28907