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DEAF1 antibody (Deformed Epidermal Autoregulatory Factor 1 (Drosophila)) (N-Term)

Details for Product anti-DEAF1 Antibody No. ABIN309945, Supplier: Login to see New
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Synonyms CG8567, DEAF-1, DEAF1, Deaf-1, Dmel\\CG8567, deaf1, l(3)76BDv, spn, nudr, zmynd5, NUDR, SPN, ZMYND5, AU042387, C230009B13Rik, MYND5
(38), (16), (8), (6), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Dog (Canine), Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Rat (Rattus)
(78), (24), (22), (1), (1)
(73), (20)
This DEAF1 antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(72), (48), (11), (6), (6), (4), (3), (2), (2), (1)
Pubmed 1 reference available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human DEAF1
Blocking Peptide Blocking peptide for this product available: ABIN975713
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Dog : 90 %, Pig : 90 %
Characteristics This is a rabbit polyclonal antibody against DEAF1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name DEAF1 (DEAF1 Antibody Abstract)
Background DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Molecular Weight 59 kDa
Gene ID 10522
NCBI Accession NP_066288, NM_021008
UniProt O75398
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 565 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-DEAF1 antibody (Deformed Epidermal Autoregulatory Factor 1 (Drosophila)) (N-Term) (ABIN309945) anti-Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (N-Term) antibody
Background publications Czesak, Lemonde, Peterson et al.: "Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 6, pp. 1864-71, 2006 (PubMed).

Catalog No. ABIN309945
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