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Details for Product No. ABIN309945

Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) (N-Term) antibody

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Antigen
Synonyms NUDR, AU042387, C230009B13Rik, SPN, ZMYND5, CG8567, DEAF-1, DEAF1, Deaf-1, Dmel\\CG8567, deaf1, l(3)76BDv, MYND5, spn, nudr, zmynd5
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Dog (Canine), Fruit Fly (Drosophila melanogaster), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN309945
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Product details

Target Details Application Details Handling References Alternatives back to top
Immunogen The immunogen for anti-DEAF1 antibody: synthetic peptide directed towards the N terminal of human DEAF1
Sequence EEPVLSRDEDSEEDADSEAERETPRVTAVAVMAAEPGHMD MGAEALPGPD
Predicted Reactivity 156577
Characteristics This is a rabbit polyclonal antibody against DEAF1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified

Target Details

Application Details Handling References Alternatives back to top
Alternative Name DEAF1
Background DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Molecular Weight 59kDa
Gene ID 10522
NCBI Accession NP_066288, NM_021008
UniProt O75398

Application Details

Target Details Handling References Alternatives back to top
Restrictions For Research Use only

Handling

Target Details Application Details References Alternatives back to top
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-DEAF1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C

References

Target Details Application Details Handling Alternatives back to top
Background publications Czesak, Lemonde, Peterson et al.: "Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 6, pp. 1864-71, 2006 (PubMed).

Alternatives

Target Details Application Details Handling References back to top
Alternatives for antigen "Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1)", type "Antibodies"
Hosts (23), (14)
Reactivities (25), (14), (12), (12), (12), (11), (11)
Applications (26), (17), (9), (3), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (2), (2), (1), (1), (1), (1), (1), (1)
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