DEAF1 antibody (AA 211-310)

Catalog No. ABIN873000

Product Details anti-DEAF1 Antibody

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Binding Specificity: AA 211-310

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEAF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Rat,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Deformed Epidermal Autoregulatory Factor 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DEAF1

Target: DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))

Alternative Name: Deformed Epidermal Autoregulatory Factor 1 (DEAF1 Products)

Synonyms: AU042387 antibody, C230009B13Rik antibody, NUDR antibody, SPN antibody, ZMYND5 antibody, MYND5 antibody, spn antibody, DEAF1 antibody, nudr antibody, zmynd5 antibody, CG8567 antibody, DEAF-1 antibody, Deaf-1 antibody, Dmel\\CG8567 antibody, deaf1 antibody, l(3)76BDv antibody, deformed epidermal autoregulatory factor 1 (Drosophila) antibody, DEAF1, transcription factor antibody, DEAF1 transcription factor antibody, deformed epidermal autoregulatory factor 1 homolog antibody, Deformed epidermal autoregulatory factor-1 antibody, Deaf1 antibody, DEAF1 antibody, LOC509260 antibody, deaf1 antibody, deaf-1 antibody

Background:

Synonyms: DEAF1, Deformed epidermal autoregulatory factor 1 homolog, Nuclear DEA1 related transcriptional regulator, NUDR, SPN, Suppressin, Zinc finger MYND domain containing protein 5, ZMYND5, DEAF1_HUMAN.

Background: Suppressin, also known as DEAF1 is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.

Gene ID: 10522

Pathways: Tube Formation