Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody

Details for Product No. ABIN310131
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Antigen
Synonyms 2810434J10Rik, 9030215G15Rik, Nkd, Naked1
Epitope
N-Term
(9), (7), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human, Chicken
(13), (4)
Host
Rabbit
(17)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(17), (6), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN310131
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human NKD1
Sequence ELVGDVLRDT LSEEEEDDFR LEVALPPEKT DGLGSGDEKK MERVSEPCPG
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Dog : 90 %, Chicken : 80 %, Bovine : 80 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against NKD1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name NKD1
Background In the mouse, Nkd is a Dishevelled -binding protein that functions as a negative regulator of the Wnt-beta-catenin -Tcf signaling pathway.In the mouse, Nkd is a Dishevelled (see DVL1, MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1, MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.
Molecular Weight 52 kDa
Gene ID 85407
NCBI Accession NP_149110, NM_033119
UniProt Q969G9
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 470 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody
anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody (2) anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody (Image 2)
Background publications Yan, Wiesmann, Rohan et al.: "Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 26, pp. 14973-8, 2001 (PubMed).

Validation Images
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