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Details for Product No. ABIN310131

Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody

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Antigen
Synonyms Naked1, Nkd, 2810434J10Rik, 9030215G15Rik
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Cow (Bovine), Human, Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN310131
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-NKD1 antibody: synthetic peptide directed towards the N terminal of human NKD1
Sequence ELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKK MERVSEPCPG
Predicted Reactivity Guinea pig : 100%, Human : 100%, Dog : 92%, Chicken : 85%, Bovine : 84%, Mouse : 84%, Rat : 84%
Characteristics This is a rabbit polyclonal antibody against NKD1. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Affinity Purified
Alternative Name NKD1
Background In the mouse, Nkd is a Dishevelled -binding protein that functions as a negative regulator of the Wnt-beta-catenin -Tcf signaling pathway.In the mouse, Nkd is a Dishevelled (see DVL1, MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1, MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.
Molecular Weight 52kDa
Gene ID 85407
NCBI Accession NP_149110, NM_033119
UniProt Q969G9
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-NKD1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Yan, Wiesmann, Rohan et al.: "Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 26, pp. 14973-8, 2001 (PubMed).

Alternatives for antigen "Naked Cuticle Homolog 1 (Drosophila) (NKD1)", type "Antibodies"
Hosts (11)
Reactivities (7), (3)
Applications (9), (2), (2), (1), (1)
Epitopes (4), (2), (1), (1), (1), (1)
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