Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody

Details for Product No. ABIN310131
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Antigen
Synonyms Naked1, Nkd, 2810434J10Rik, 9030215G15Rik
Epitope
N-Term
(3), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Human, Chicken
(7), (2)
Host
Rabbit
(11)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(9), (2), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN310131
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide directed towards the N terminal of human NKD1
Sequence ELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKK MERVSEPCPG
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Dog : 90 %, Chicken : 80 %, Bovine : 80 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against NKD1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name NKD1
Background In the mouse, Nkd is a Dishevelled -binding protein that functions as a negative regulator of the Wnt-beta-catenin -Tcf signaling pathway.In the mouse, Nkd is a Dishevelled (see DVL1, MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1, MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.
Molecular Weight 52 kDa
Gene ID 85407
NCBI Accession NM_033119, NP_149110
UniProt Q969G9
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 470 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody
anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody (2) anti-Naked Cuticle Homolog 1 (Drosophila) (NKD1) (N-Term) antibody (Image 2)
Background publications Yan, Wiesmann, Rohan et al.: "Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 26, pp. 14973-8, 2001 (PubMed).

Hosts (11)
Reactivities (7), (2)
Applications (9), (2), (2), (1)
Epitopes (3), (2), (1), (1), (1), (1)
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