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STEAP3 antibody (N-Term)

STEAP3 Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN310477
  • Target See all STEAP3 Antibodies
    STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
    Binding Specificity
    • 11
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 40
    • 16
    • 16
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit, Pig
    Host
    • 40
    Rabbit
    Clonality
    • 40
    Polyclonal
    Conjugate
    • 19
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STEAP3 antibody is un-conjugated
    Application
    • 29
    • 21
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LVGSGFKVVV GSRNPKRTAR LFPSAAQVTF QEEAVSSPEV IFVAVFREHY
    Predicted Reactivity
    Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human STEAP3
    Top Product
    Discover our top product STEAP3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 488 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
    Alternative Name
    STEAP3 (STEAP3 Products)
    Synonyms
    STEAP3 antibody, 1010001D01Rik antibody, Tsap6 antibody, pHyde antibody, AHMIO2 antibody, STMP3 antibody, TSAP6 antibody, dudlin-2 antibody, STEAP3 metalloreductase antibody, STEAP family member 3 antibody, STEAP3 antibody, steap3 antibody, Steap3 antibody
    Background
    AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT
    Alias Symbols: STMP3, TSAP6, dudlin-2
    Protein Interaction Partner: UBC, SETD7, BAD, TPT1, BNIP3L, PKMYT1,
    Protein Size: 488
    Molecular Weight
    54 kDa
    Gene ID
    55240
    NCBI Accession
    NM_001008410, NP_001008410
    UniProt
    Q658P3
    Pathways
    Transition Metal Ion Homeostasis
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