STEAP3 antibody (AA 421-470)

Catalog No. ABIN1533955

The Rabbit Polyclonal anti-STEAP3 antibody is suitable to detect STEAP3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for STEAP3 antibody (AA 421-470) (ABIN1533955)

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-STEAP3 Antibody

Binding Specificity: AA 421-470

Purpose: pHyde Antibody

Specificity:  pH yde Polyclonal Antibody detects endogenous levels of pH yde protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human STEA3. AA range:421-470

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Background:

Synonyms: STEAP3, TSAP6, Metalloreductase STEAP3, Dudulin-2, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, hTSAP6, pH yde, h pH yde

Background: STEAP3 metalloreductase(STEAP3) Homo sapiens This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Gene Name: STEAP3

Protein Name: Metalloreductase STEAP3

Molecular Weight: 54 kDa

Gene ID: 55240

OMIM: 609671

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis