CDGSH Iron Sulfur Domain 2 (CISD2) (N-Term) antibody

Details for Product No. ABIN310609
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Antigen
Synonyms
eris, miner1, wfs2, zcd2, ZCD2, zgc:64148, cisd2, ERIS, Miner1, NAF-1, WFS2, 1500009M05Rik, 1500026J14Rik, 1500031D15Rik, AI848398, B630006A20Rik, Noxp70, Zcd2, RGD1566242, RGD1306802, ABIN, ABIN-1, A ... show more
eris, miner1, wfs2, zcd2, ZCD2, zgc:64148, cisd2, ERIS, Miner1, NAF-1, WFS2, 1500009M05Rik, 1500026J14Rik, 1500031D15Rik, AI848398, B630006A20Rik, Noxp70, Zcd2, RGD1566242, RGD1306802, ABIN, ABIN-1, ABIN1, AU018810, Naf1, Nef, VAN show less
Epitope
N-Term
(3), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Xenopus laevis, Zebrafish (Danio rerio), Human
(7), (3), (3)
Host
Rabbit
(7)
Clonality
Polyclonal
Application
Western Blotting (WB)
(7), (3), (3), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN310609
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human CISD2
Sequence VLESVARIVK VQLPAYLKRL PVPESITGFA RLTVSEWLRL LPFLGVLALL
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against CISD2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CISD2
Background CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. It binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2 (WFS2).
Molecular Weight 15 kDa
Gene ID 493856
NCBI Accession NP_001008389, NM_001008388
UniProt Q8N5K1
Research Area Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 135 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Amr, Heisey, Zhang et al.: "A homozygous mutation in a novel zinc-finger protein, ERIS, is responsible for Wolfram syndrome 2." in: American journal of human genetics, Vol. 81, Issue 4, pp. 673-83, 2007 (PubMed).

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