Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3) (N-Term) antibody

Details for Product No. ABIN310758
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Synonyms EIF2S3, eif2, eif2g, eif2s3y, eif2gamma, Su(var)3-9, fi03g03, wu:fi03g03, wu:fi37d04, zgc:63805, EIF2, EIF2G, EIF2gamma, eIF-2gA, Eif2g, Eif2s3, PP42, ENSMUSG00000079297
(15), (14), (5), (3), (2), (2), (1)
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(40), (9), (8), (3), (1), (1), (1), (1), (1)
(33), (7)
(2), (2), (2), (2), (2), (2)
Western Blotting (WB)
(39), (23), (10), (3), (3), (2), (1)
Pubmed 1 reference available
Quantity 100 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human EIF2S3
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Zebrafish : 100 %, African clawed frog : 90 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against EIF2S3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name EIF2S3 (EIF2S3 Antibody Abstract)
Background EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Molecular Weight 51 kDa
Gene ID 1968
NCBI Accession NM_001415, NP_001406
UniProt P41091
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 472 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3) (N-Term) antibody (ABIN310758) WB Suggested Anti-EIF2S3 Antibody Titration: 5.0ug/ml
Positive Control: ...
Background publications Gevaert, Goethals, Martens et al.: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).

Catalog No. ABIN310758
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