anti-CDT1 antibody (Chromatin Licensing and DNA Replication Factor 1) (C-Term)

Details for Product anti-CDT1 Antibody No. ABIN310811
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Synonyms CDT1, fc37h07, im:7158083, wu:fc37h07, wu:fi38h09, xcdt1, DUP, RIS2, 2610318F11Rik, AW545653, C76791, Ris2, dup, ris2
(23), (1), (1), (1), (1)
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(42), (6), (6)
(21), (19), (2)
This CDT1 antibody is un-conjugated
(1), (1), (1), (1), (1), (1)
Immunohistochemistry (IHC), Western Blotting (WB)
(39), (22), (4), (4), (3), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the C terminal of human CDT1
Predicted Reactivity Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Bovine : 90 %, Rabbit : 90 %
Characteristics This is a rabbit polyclonal antibody against CDT1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CDT1 (CDT1 Antibody Abstract)
Background CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.
Molecular Weight 60 kDa
Gene ID 81620
NCBI Accession NP_112190, NM_030928
UniProt Q9H211
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA
Pathways MAPK Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 546 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-CDT1 antibody (Chromatin Licensing and DNA Replication Factor 1) (C-Term) (ABIN310811) WB Suggested Anti-CDT1 Antibody Titration: 0.2-1 ug/ml
Positive Control:...
Western Blotting (WB) image for anti-CDT1 antibody (Chromatin Licensing and DNA Replication Factor 1) (C-Term) (ABIN310811) Sample Type: 3. rat brain extract (80ug)
Primary Antibody Dilution:...
Background publications Hu, Xiong: "An evolutionarily conserved function of proliferating cell nuclear antigen for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage." in: The Journal of biological chemistry, Vol. 281, Issue 7, pp. 3753-6, 2006 (PubMed).

Catalog No. ABIN310811
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