Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibody

Details for Product No. ABIN310846
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Synonyms MPR, HPR6.6, PPMR, Vema, AA415812, 25Dx, VEMA, 25-Dx, MGC89150, wu:fa94d03, zgc:103577, DKFZp469D0815
(3), (1)
Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine), Human
(11), (4), (4)
(6), (5), (2)
Immunohistochemistry (IHC), Western Blotting (WB)
(12), (6), (5), (1)
Pubmed 1 reference available
Catalog no. ABIN310846
Quantity 50 µg
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Immunogen Synthetic peptide directed towards the N terminal of human PGRMC1
Predicted Reactivity Human : 100 %, Mouse : 90 %, Rat : 90 %, Dog : 80 %, Horse : 80 %, Rabbit : 80 %, Bovine : 70 %
Characteristics This is a rabbit polyclonal antibody against PGRMC1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name PGRMC1
Background Progesterone binding protein is a putative steroid membrane receptor. The protein is expressed predominantly in the liver and kidney.Progesterone binding protein is a putative steroid membrane receptor. The protein is expressed predominantly in the liver and kidney.
Molecular Weight 22 kDa
Gene ID 10857
NCBI Accession NM_006667, NP_006658
UniProt O00264
Research Area Cancer
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 195 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
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anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibody WB Suggested Anti-PGRMC1 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Background publications Peluso, Liu, Saunders et al.: "Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 5, pp. 1592-9, 2008 (PubMed).

Hosts (6), (5), (2)
Reactivities (11), (4), (4)
Applications (12), (6), (5), (1)
Epitopes (3), (1)
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