Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibody

Details for Product No. ABIN310846
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Antigen
Synonyms MGC89150, wu:fa94d03, zgc:103577, DKFZp469D0815, HPR6.6, MPR, AA415812, PPMR, Vema, 25-Dx, 25Dx, VEMA
Epitope
N-Term
(3), (2), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine), Human
(12), (4), (4)
Host
Rabbit
(6), (4), (2)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(12), (6), (5), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN310846
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human PGRMC1
Sequence MAAEDVVATG ADPSDLESGG LLHEIFTSPL NLLLLGLCIF LLYKIVRGDQ
Predicted Reactivity Human : 100 %, Mouse : 90 %, Rat : 90 %, Dog : 80 %, Horse : 80 %, Rabbit : 80 %, Bovine : 70 %
Characteristics This is a rabbit polyclonal antibody against PGRMC1. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name PGRMC1
Background Progesterone binding protein is a putative steroid membrane receptor. The protein is expressed predominantly in the liver and kidney.Progesterone binding protein is a putative steroid membrane receptor. The protein is expressed predominantly in the liver and kidney.
Molecular Weight 22 kDa
Gene ID 10857
NCBI Accession NP_006658, NM_006667
UniProt O00264
Research Area Cancer
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 195 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Progesterone Receptor Membrane Component 1 (PGRMC1) (N-Term) antibody WB Suggested Anti-PGRMC1 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Background publications Peluso, Liu, Saunders et al.: "Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 5, pp. 1592-9, 2008 (PubMed).

Validation Images
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