Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) (Middle Region) antibody

Details for Product No. ABIN311477
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Antigen
Synonyms AW208766, Brp39, Gp39, ASRT7, CGP-39, GP-39, GP39, HC-gp39, HCGP-3P, YKL-40, YKL40, YYL-40, hCGP-39, GP38K, CLP-1, SPC-40, SPS-40, Chil1, BP40, MGP-40
Epitope
Middle Region
(13), (8), (6), (5), (2), (1), (1), (1), (1)
Reactivity
Rat (Rattus), Cow (Bovine), Pig (Porcine), Human
(50), (7), (7)
Host
Rabbit
(29), (22)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(38), (26), (16), (6), (5), (3), (2), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN311477
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human CHI3L1
Sequence LDFISIMTYD FHGAWRGTTG HHSPLFRGQE DASPDRFSNT DYAVGYMLRL
Predicted Reactivity Human : 100 %, Rabbit : 100 %, Pig : 80 %, Rat : 70 %
Characteristics This is a rabbit polyclonal antibody against CHI3L1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CHI3L1
Background CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment. CHI3L1 may play a role in tissue remodeling and defense against pathogens. It belongs to the glycosyl hydrolase 18 family. CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment.
Molecular Weight 42 kDa
Gene ID 1116
NCBI Accession NP_001267, NM_001276
UniProt P36222
Research Area Signaling, Extracellular Matrix, Cancer
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 383 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) (Middle Region) antibody WB Suggested Anti-CHI3L1 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
Background publications Ober, Tan, Sun et al.: "Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function." in: The New England journal of medicine, Vol. 358, Issue 16, pp. 1682-91, 2008 (PubMed).

Validation Images
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