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Details for Product No. ABIN317544

Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) (AA 383-660) antibody

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Antigen
Synonyms NSD3, pp14328, 6720429E03, A530023P05, AI528490, WHISTLE, WHSC1L1
Epitope
»Alternatives AA 383-660
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN317544
Quantity 0.1 mL
Price
401.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant human NSD3 (383-660 aa) purified from E. coli
Clone 2E9
Isotype IgG2b
Characteristics Synonyms: Wolf-Hirschhorn syndrome candidate 1-like protein 1, Whistle, DC28, Histone-lysineN-methyltransferase NSD3, Nuclear SET domain-containing protein 3, WHSC1-like protein 1,WHSC1-like 1 isoform 9 with methyltransferase activity to lysine
Purification Protein-G Affinity Chromatography
Alternative Name WHSC1L1 / NSD3
Background This gene encoding NSD3 is related to the Wolf-Hirschhorn syndrome candidate - 1 geneand encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. NSD3is a Histone methyltransferase which preferentially methylates 'Lys-4' and 'Lys-27' ofhistone H3 and is amplified in several tumor cell lines and primary breast carcinomas.
UniProt Q9BZ95
Application Notes ELISA. Western blot (1: 1,000 - 1: 3,000), recommended starting dilution is 1: 2,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4 0.09% Sodium Azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Stec, Nagl, van Ommen et al.: "The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?" in: FEBS letters, Vol. 473, Issue 1, pp. 1-5, 2000 (PubMed).

Angrand, Apiou, Stewart et al.: "NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines." in: Genomics, Vol. 74, Issue 1, pp. 79-88, 2001 (PubMed).

Alternatives for antigen "Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1)", type "Antibodies"
Hosts (19), (15)
Reactivities (36), (5), (5), (3)
Applications (31), (15), (4), (3), (1), (1)
Epitopes (5), (4), (2), (2), (1)
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