Integrin beta 3 (ITGB3) antibody (PE)

Details for Product No. ABIN319520
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Antigen
Synonyms BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT, INGRB3, integrin
Reactivity
Human
(300), (165), (80), (48), (43), (26), (26), (9), (6), (3), (1), (1), (1), (1), (1)
Host
Mouse
(168), (156), (49), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
PE
(53), (27), (22), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(183), (171), (74), (67), (55), (48), (36), (30), (16), (12), (8), (6), (1)
Pubmed 3 references available
Catalog no. ABIN319520
Quantity 100 tests
Price
434.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen PHA stimulated peripheral blood cells. Spleen cells from immunised Balb/c mice were fused with cells of the NS1 myeloma cell line.
Clone Y2-51
Isotype IgG1
Specificity This antibody recognises CD61.
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Alternative Name CD61 / ITGB3
Background CD61 is a 105kD glycoprotein, which is also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.
Alternate names: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
NCBI Accession 9606
UniProt P05106
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: Use 10 l of neat antibody to label 10e6 cells in 100 l. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 1.0 mL distilled water.
Concentration 0.1mg/mL
Buffer PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Preservative Sodium azide
Handling Advice Dilute only prior to immediate use
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
Expiry Date 12 months
Background publications Hynes: "Integrins: versatility, modulation, and signaling in cell adhesion." in: Cell, Vol. 69, Issue 1, pp. 11-25, 1992 (PubMed).

Phillips, Charo, Scarborough: "GPIIb-IIIa: the responsive integrin." in: Cell, Vol. 65, Issue 3, pp. 359-62, 1991 (PubMed).

Gatter, Cordell, Turley et al.: "The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens." in: Histopathology, Vol. 13, Issue 3, pp. 257-67, 1989 (PubMed).

Hosts (168), (156), (49), (2), (1)
Reactivities (300), (165), (80), (48), (43), (26), (26), (9), (6), (3), (1), (1), (1), (1), (1)
Applications (183), (171), (74), (67), (55), (48), (36), (30), (16), (12), (8), (6), (1)
Conjugates (53), (27), (22), (7), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Epitopes (37), (36), (14), (5), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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