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Details for Product No. ABIN334499

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (C-Term) antibody

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Antigen
Synonyms ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, SUR1delta2, TNDM2, Sur, Sur1, D930031B21Rik
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN334499
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Availability Ships within 5 Business Days
Immunogen Peptide with sequence C-EFDKPEKLLSRKD, from the C Terminus of the protein sequence according to NP_000343.2.
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name SUR1 / ABCC8
Background Synonyms: ABCC8, SUR1, ATP-binding cassette, sub-family C (CFTR/MRP), member 8, ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, TNDM2, ATP-binding cassette, sub-family C, member 8, sulfonylurea receptor (hyperinsulinemia)
Gene ID 6833, 20927, 25559
NCBI Accession NP_000343.2
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: Approx 170 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177 kDa according to NP_000343.2). Recommended concentration: 0.5-1.5 µg/mL. An additional band of unknown identity was also consistently observed at 23 kDa. This band was successfully blocked by incubation with the immunising peptide.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
de Wet, Rees, Shimomura et al.: "Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 48, pp. 18988-92, 2007 (PubMed).

Alternatives for antigen "ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8)", type "Antibodies"
Hosts (24), (12), (4)
Reactivities (31), (23), (22), (18), (17), (17), (2), (1)
Applications (22), (15), (13), (10), (7), (4), (2), (2), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (3), (2), (2)
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