ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (C-Term) antibody

Details for Product No. ABIN334499
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Antigen
Synonyms ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, SUR1delta2, TNDM2, Sur, Sur1, D930031B21Rik
Epitope
C-Term
(4), (4), (2), (2), (1), (1), (1)
Reactivity
Human
(33), (23), (22), (18), (17), (17), (2), (2), (1)
Host
Goat
(26), (13), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(24), (14), (12), (10), (9), (4), (2), (2), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN334499
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
Options
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide with sequence C-EFDKPEKLLSRKD, from the C Terminus of the protein sequence according to NP_000343.2.
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name SUR1 / ABCC8
Background Synonyms: ABCC8, SUR1, ATP-binding cassette, sub-family C (CFTR/MRP), member 8, ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, TNDM2, ATP-binding cassette, sub-family C, member 8, sulfonylurea receptor (hyperinsulinemia)
Gene ID 6833, 20927, 25559
NCBI Accession NP_000343.2
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: Approx 170 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177 kDa according to NP_000343.2). Recommended concentration: 0.5-1.5 µg/mL. An additional band of unknown identity was also consistently observed at 23 kDa. This band was successfully blocked by incubation with the immunising peptide.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (C-Term) antibody ABIN334499 (0.5µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
General de Wet, Rees, Shimomura et al.: "Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 48, pp. 18988-92, 2007 (PubMed).

Hosts (26), (13), (3)
Reactivities (33), (23), (22), (18), (17), (17), (2), (2), (1)
Applications (24), (14), (12), (10), (9), (4), (2), (2), (1), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (4), (2), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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