Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN350196

Caveolin 1, Caveolae Protein (CAV1) (1st Cytoplasmic Domain) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms Cav, Cav-1
Epitope
»Alternatives 1st Cytoplasmic Domain
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350196
Quantity 500 µg
Price
454.67 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from the 1t cytoplasmic domain of human Caveolin-1 (CAV1, CAV) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in many other species including rat, mouse.
Isotype IgG
Specificity Appears to be specific for Caveolin-1.
Purity IgG
Alternative Name Caveolin-1 (CAV1, CAV)
Background Function: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
Subcellular location: Golgi apparatus membrane, Single-pass membrane protein. Cell membrane, Single-pass membrane protein. Note: Potential hairpin-like structure in the membrane. Membrane protein of protein of caveolae.
Tissue specificity: In muscle and lung, less so in liver, brain and kidney. Also known as: CAV1, CAV.
UniProt Q03135
Application Notes IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Eberle, Serrano, Fuellekrug et al.: "Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex." in: Journal of cell science, Vol. 115, Issue Pt 4, pp. 827-38, 2002 (PubMed).

Aboulaich, Vainonen, Strålfors et al.: "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes." in: The Biochemical journal, Vol. 383, Issue Pt 2, pp. 237-48, 2004 (PubMed).

Schilling, Opitz, Wiesenthal et al.: "Translocation of endothelial nitric-oxide synthase involves a ternary complex with caveolin-1 and NOSTRIN." in: Molecular biology of the cell, Vol. 17, Issue 9, pp. 3870-80, 2006 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Dephoure, Zhou, Villén et al.: "A quantitative atlas of mitotic phosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 31, pp. 10762-7, 2008 (PubMed).

Alternatives for antigen "Caveolin 1, Caveolae Protein (CAV1)", type "Antibodies"
Hosts (2), (1)
Reactivities (3), (3), (3)
Applications (3), (3)
Epitopes (3)
Beacon