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Caveolin-1 Products

(Caveolin 1, Caveolae Protein, 22kDa (CAV1))

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The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010].

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Featured Caveolin-1 Categories

Caveolin-1 Antibodies

High quality antibodies with extensive validation data.

Caveolin-1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Caveolin-1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Caveolin-1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP, IHC (p), ICC
Validations
  • (1)
  • (7)
Cat. No. ABIN2854651
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7431320
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7431323
Quantity 100 μL
Datasheet Datasheet

Recommended Caveolin-1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (1)
Cat. No. ABIN6954474
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954475
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6954472
Quantity 96 tests
Datasheet Datasheet

Recommended Caveolin-1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (4)
  • (1)
Cat. No. ABIN1348146
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
  • (2)
Cat. No. ABIN7538162
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122185
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Caveolin-1 products

Yang, Ma, Wei, Ye, Zhou, Wen, Men, Aqeilan, Peng, Yang: "Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 75, (2021) (PubMed).

Fang, Lin, Liang, Liang: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).

Yada, Shimokawa, Tachibana et al.: "Endothelium-dependent hyperpolarization-mediated vasodilatation compensates nitric oxide-mediated endothelial dysfunction during ischemia in diabetes-induced canine coronary collateral ..." in: Microcirculation (New York, N.Y. : 1994), Vol. 25, Issue 5, pp. e12456, (2019) (PubMed).

Arima, Cui, Kimura, Sonoda, Ishibashi, Matsuda, Ikeda: "Basigin can be a therapeutic target to restore the retinal vascular barrier function in the mouse model of diabetic retinopathy." in: Scientific reports, Vol. 6, pp. 38445, (2018) (PubMed).

Li, Scott, Fan, Li, Liu, Xiao, Li, Billiar, Wilson, Jiang, Fan: "Tissue damage negatively regulates LPS-induced macrophage necroptosis." in: Cell death and differentiation, Vol. 23, Issue 9, pp. 1428-47, (2018) (PubMed).

Flis, Dzik, Kaczor, Halon-Golabek, Antosiewicz, Wieckowski, Ziolkowski: "Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis Mice." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 5940748, (2018) (PubMed).

Eliyatkin, Aktas, Diniz, Ozgur, Ekin, Kupelioglu: "Expression of Stromal Caveolin- 1 May Be a Predictor for Aggressive Behaviour of Breast Cancer." in: Pathology oncology research : POR, (2017) (PubMed).

Gao, Chen, Peng, Yang, Wang, Lv, Shen: "Caveolin-1 protects against hepatic ischemia/reperfusion injury through ameliorating peroxynitrite-mediated cell death." in: Free radical biology & medicine, Vol. 95, pp. 209-15, (2017) (PubMed).

Platas, Guillén, Pérez Del Caz, Gomar, Castejón, Mirabet, Alcaraz: "Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes." in: Aging, Vol. 8, Issue 8, pp. 1703-17, (2017) (PubMed).

Liu, Liu, Yu, Gu: "A preliminary study on the interaction between Asn-Gly-Arg (NGR)-modified multifunctional nanoparticles and vascular epithelial cells." in: Acta pharmaceutica Sinica. B, Vol. 7, Issue 3, pp. 361-372, (2017) (PubMed).

Synonyms and alternative names related to Caveolin-1

caveolin 1 (cav1), caveolin 1 L homeolog (cav1.L), caveolin 1 S homeolog (cav1.S), caveolin 1 (CAV1), caveolin 1, caveolae protein (Cav1), caveolin 1 (Cav1), caveolin 1, caveolae protein, 22kDa (CAV1), Caveolin (cav-1), bscl3, BSCL3, cav, Cav, Cav-1, cav-1, cav1, CAV1, cav1a, cav1b, caveolin-1, Caveolin-1, caveolin 1, cgl3, CGL3, fc07c04, mstp085, MSTP085, PPH3, vip21, VIP21, wu:fc07c04

Protein level used designations for Caveolin-1

  • caveolin-1
  • caveolin 1
  • caveolin, caveolae protein 1
  • caveolin, caveolae protein, 22 kDa
  • caveolin caveolae protein 22 kDa
  • vesicular integral-membrane protein VIP21
  • cell growth-inhibiting protein 32
  • testis derived transcript
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