You are viewing an incomplete version of our website. Please click to reload the website as full version.

Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1) (AA 170-220) antibody

Details for Product No. ABIN350338, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms 4930406E12Rik, AU016030, AW209092, fb33h10, im:6912200, wu:fb33h10, zgc:101044
AA 170-220
(23), (16), (5), (5), (5), (2), (1), (1), (1)
Mouse (Murine), Rat (Rattus), Human
(56), (20), (15), (2), (1), (1)
(50), (9)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (IHC), Western Blotting (WB)
(44), (26), (11), (10), (8), (7), (2), (2), (2), (1)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 500 μg
Shipping to United States ( )
Availability Will be delivered in 7 to 8 Business Days
Immunogen A synthetic peptide from aa region 170-220 of the GAT domain of human GGA1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in many other species including rat, mouse, xenopus, zebrafish.
Isotype IgG
Specificity Specific for GGA1.
Alternative Name GGA1 (GGA1 Antibody Abstract)
Background Function: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
Subcellular location: Golgi apparatus, trans-Golgi network membrane, Peripheral membrane protein. Endosome membrane, Peripheral membrane protein.
Tissue specificity: Ubiquitously expressed. Also known as: ADP-ribosylation factor-binding protein GGA1, Golgi-localized, gamma ear-containing, ARF-binding protein 1, Gamma-adaptin-related protein 1.
Research Area Signaling
Application Notes A concentration of 10-50 µg/ml is recommended.
The optimal concentration should be determined by the end user. Not tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

He, Zhu, Koelsch et al.: "Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins." in: Biochemistry, Vol. 42, Issue 42, pp. 12174-80, 2003 (PubMed).

Boman, Zhang, Zhu et al.: "A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-Golgi." in: Molecular biology of the cell, Vol. 11, Issue 4, pp. 1241-55, 2000 (PubMed).

DellAngelica, Puertollano, Mullins et al.: "GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex." in: The Journal of cell biology, Vol. 149, Issue 1, pp. 81-94, 2000 (PubMed).

Dunham, Shimizu, Roe et al.: "The DNA sequence of human chromosome 22. ..." in: Nature, Vol. 402, Issue 6761, pp. 489-95, 1999 (PubMed).

Catalog No. ABIN350338
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)