GGA1 Products
(Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 1 (GGA1))
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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured GGA1 Categories
GGA1 Antibodies
High quality antibodies with extensive validation data.
GGA1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GGA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN565221
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN565222
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF
Validations
- (1)
- (2)
Cat. No.
ABIN389018
Quantity
400 μL
Datasheet
Datasheet
Recommended GGA1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6212537
Quantity
96 tests
Datasheet
Datasheet
Recommended GGA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355037
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3080754
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3126561
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GGA1 products
: "GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 39, pp. 9913-22, (2006) (PubMed).: "Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport." in: Nature structural biology, Vol. 10, Issue 5, pp. 386-93, (2003) (PubMed).
: "Crystal structure of the human GGA1 GAT domain." in: Biochemistry, Vol. 42, Issue 21, pp. 6392-9, (2003) (PubMed).
: "The interaction of the human GGA1 GAT domain with rabaptin-5 is mediated by residues on its three-helix bundle." in: Biochemistry, Vol. 42, Issue 47, pp. 13901-8, (2003) (PubMed).
Synonyms and alternative names related to GGA1
putative golgi associated, gamma adaptin ear containing,arf binding protein 1 (gga1) (Smp_164030), golgi associated, gamma adaptin ear containing, ARF binding protein 1 (Gga1), golgi-associated, gamma adaptin ear containing, ARF binding protein 1 (gga1), golgi associated, gamma adaptin ear containing, ARF binding protein 1 (GGA1), 4930406E12Rik, AU016030, AW209092, fb33h10, im:6912200, wu:fb33h10, zgc:101044Protein level used designations for GGA1
- golgi associated gamma adaptin ear containing arf binding protein 1 (gga1)
- ADP-ribosylation factor-binding protein GGA1
- gamma-adaptin-related protein 1
- golgi-localized, gamma ear-containing, ARF-binding protein 1
- ADP-ribosylation factor binding protein 1
- gamma-adaptin related protein 1
- golgi associated, gamma adaptin ear containing, ARF binding protein 1
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