RAB5A, Member RAS Oncogene Family (RAB5A) (Internal Region) antibody

Details for Product No. ABIN350782
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Antigen
Synonyms DDBDRAFT_0168594, DDBDRAFT_0229401, DDB_0168594, DDB_0229401, rab5, RAB5A, RAB5, 2410015H04Rik, AI663973, AU021172, nnyRab5a
Epitope
Internal Region
(15), (13), (9), (7), (6), (6), (3), (2), (2), (2), (2), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus)
(110), (59), (44), (22), (19), (14), (9), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Host
Sheep
(91), (25), (4), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(106), (27), (25), (22), (11), (10), (10), (10), (7), (3), (1), (1)
Pubmed 2 references available
Quantity 500 μg
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Catalog No. ABIN350782
454.67 $
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Immunogen A synthetic peptide from the internal region of mouse Ras-related protein Rab-5A (RAB5A) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in rat.
Isotype IgG
Specificity Specific for RAB5A.
Alternative Name RAB5A
Background Function: Required for the fusion of plasma membranes and early endosomes.
Enzyme regulation: Regulated by guanine nucleotide exchange factors (GEFs) which promote the
Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Early endosome membrane, Lipid-anchor. Melanosome. Also known as: RAB5A.
Research Area Signaling
Application Notes Use at a concentration of 10-50 µg/ml.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
General Yang, Sasaki, Minoshima et al.: "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway." in: Genomics, Vol. 90, Issue 2, pp. 249-60, 2007 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome. ..." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).

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