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RAB5 antibody (RAB5A, Member RAS Oncogene Family) (Internal Region)

Details for Product anti-RAB5A Antibody No. ABIN350782, Supplier: Login to see
Antigen
  • DDBDRAFT_0168594
  • DDBDRAFT_0229401
  • DDB_0168594
  • DDB_0229401
  • rab5
  • RAB5A
  • RAB5
  • 2410015H04Rik
  • AI663973
  • AU021172
  • nnyRab5a
Epitope
Internal Region
26
19
14
9
8
6
4
3
3
3
2
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
166
80
70
27
26
11
3
3
2
2
2
2
2
2
2
2
2
2
Host
Sheep
145
22
5
2
Clonality
Polyclonal
Conjugate
This RAB5 antibody is un-conjugated
7
7
6
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
152
61
60
44
32
21
18
11
11
2
1
Supplier
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Immunogen A synthetic peptide from the internal region of mouse Ras-related protein Rab-5A (RAB5A) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in rat.
Isotype IgG
Specificity Specific for RAB5A.
Alternative Name RAB5A (RAB5A Antibody Abstract)
Background Function: Required for the fusion of plasma membranes and early endosomes.
Enzyme regulation: Regulated by guanine nucleotide exchange factors (GEFs) which promote the
Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Early endosome membrane, Lipid-anchor. Melanosome. Also known as: RAB5A.
Research Area Signaling
Pathways
Application Notes Use at a concentration of 10-50 µg/ml.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date 12 months
Background publications Yang, Sasaki, Minoshima et al.: "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway." in: Genomics, Vol. 90, Issue 2, pp. 249-60, 2007 (PubMed).

Carninci, Kasukawa, Katayama et al.: "The transcriptional landscape of the mammalian genome. ..." in: Science (New York, N.Y.), Vol. 309, Issue 5740, pp. 1559-63, 2005 (PubMed).