RAB5 antibody (Internal Region)

Catalog No. ABIN350782

Product Details anti-RAB5 Antibody

Target: RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Binding Specificity: Internal Region

Reactivity: Mouse

Host: Sheep

Clonality: Polyclonal

Conjugate: This RAB5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for RAB5A.

Cross-Reactivity: Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from the internal region of mouse Ras-related protein Rab-5A (RAB5A) conjugated to an immunogenic carrier protein has been used as the immunogen. The antigen is homologous in rat.

Isotype: IgG

Application Details

Application Notes: IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for RAB5

Target: RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Alternative Name: RAB5A (RAB5A Products)

Background: FUNCTION: Required for the fusion of plasma membranes and early endosomes. ENZYME REGULATION: Regulated by guanine nucleotide exchange factors (GEFs) which promote the SUBCELLULAR LOCATION: Cell membrane, Lipid-anchor, Cytoplasmic side. Early endosome membrane, Lipid-anchor. Melanosome.,Rab Family,RAB5A

UniProt: Q9CQD1

Pathways: Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity