You are viewing an incomplete version of our website. Please click to reload the website as full version.

K(lysine) Acetyltransferase 2A (KAT2A) (N-Term) antibody

Details for Product No. ABIN356619, Supplier: Log in to see
Antigen
  • KAT2A
  • GCN5L2
  • GCN5
  • PCAF-b
  • hGCN5
  • 1110051E14Rik
  • AW212720
  • Gcn5
  • Gcn5l2
  • mmGCN5
Epitope
N-Term
25
17
8
6
4
3
3
3
2
1
1
1
1
1
1
1
1
Reactivity
Human
82
16
6
2
Host
Rabbit
58
24
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
69
41
10
8
6
4
4
3
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human GCN5.
Isotype Ig
Specificity This antibody is specific to GCN5 (N-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name KAT2A / GCN5L2 (KAT2A Antibody Abstract)
Background GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. This protein has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles.Synonyms: General control of amino acid synthesis protein 5-like 2, HGCN5, Histone acetyltransferase GCN5, Histone acetyltransferase KAT2A, HsGCN5, Lysine acetyltransferase 2A, STAF97
Gene ID 2648, 9606
UniProt Q92830
Pathways
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
 image for anti-K(lysine) Acetyltransferase 2A (KAT2A) (N-Term) antibody (ABIN356619) anti-K(lysine) Acetyltransferase 2A (KAT2A) (N-Term) antibody
Background publications Sabò, Lusic, Cereseto et al.: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, 2008 (PubMed).

Wiper-Bergeron, Salem, Tomlinson et al.: "Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 8, pp. 2703-8, 2007 (PubMed).

Oishi, Kitagawa, Wada et al.: "An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification." in: The Journal of biological chemistry, Vol. 281, Issue 1, pp. 20-6, 2006 (PubMed).

Kikuchi, Takami, Nakayama: "GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes." in: Gene, Vol. 347, Issue 1, pp. 83-97, 2005 (PubMed).