KAT2A antibody (AA 1-100)

Catalog No. ABIN1679964

The Rabbit Polyclonal anti-KAT2A antibody (ABIN1679964) specifically detects KAT2A in WB and IF. The antibody is reactive with Human samples.

Quick Overview for KAT2A antibody (AA 1-100) (ABIN1679964)

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-KAT2A Antibody

Binding Specificity: AA 1-100

Sequence: MAEPSQAPTP APAAQPRPLQ SPAPAPTPTP APSPASAPIP TPTPAPAPAP AAAPAGSTGT GGPGVGSGGA GSGGDPARPG LSQQQRASQR KAQVRGLPRA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human KAT2A (NP_066564.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: KAT2A

Background: KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009],KAT2A,GCN5,GCN5L2,PCAF-b,hGCN5,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,Nuclear Receptor Signaling,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,KAT2A

Molecular Weight: 94 kDa

Gene ID: 2648

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation