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Details for Product No. ABIN357707

Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody

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Antigen
Synonyms FACE-1, FACE1, HGPS, PRO1, STE24, Ste24p, MADB, Face-1, D030046F19, A530043O15Rik, fi45a02, zgc:55655, wu:fi45a02, F2N1.21, F2N1_21, DDBDRAFT_0189115, DDBDRAFT_0237846, DDB_0189115, DDB_0237846
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN357707
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ZMPSTE24.
Specificity This antibody is specific to ZMPSTE24 (Center).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ZMPSTE24
Background ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alternate names: CAAX prenyl protease 1 homolog, FACE-1, FACE1, Farnesylated proteins-converting enzyme 1, Prenyl protein-specific endoprotease 1, STE24, Zinc metalloproteinase Ste24 homolog
Molecular Weight 54813 Da
Gene ID 10269
NCBI Accession 5874
UniProt O75844
Research Area Proteolysis / Ubiquitin, Cytoskeleton
Application Notes ELISA: 1/1,000. Western Blot: 1/100-1/500. (See Ref.1)Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Corrigan, Kuszczak, Rusinol et al.: "Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24." in: The Biochemical journal, Vol. 387, Issue Pt 1, pp. 129-38, 2005 (PubMed).

Alternatives for antigen "Zinc Metalloproteinase, Ste24 (Zmpste24)", type "Antibodies"
Hosts (43), (6)
Reactivities (45), (17), (12), (3), (3), (1)
Applications (45), (10), (5), (4)
Conjugates (4), (4), (2), (1), (1)
Epitopes (16), (7), (4), (2), (2), (2), (2), (1), (1)
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