Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody

Details for Product No. ABIN357707
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Antigen
Synonyms FACE-1, FACE1, HGPS, PRO1, STE24, Ste24p, MADB, Face-1, D030046F19, A530043O15Rik, fi45a02, zgc:55655, wu:fi45a02, F2N1.21, F2N1_21, DDBDRAFT_0189115, DDBDRAFT_0237846, DDB_0189115, DDB_0237846
Epitope
Middle Region
(14), (7), (4), (2), (2), (2), (1)
Reactivity
Human, Mouse (Murine)
(31), (10), (8), (3), (1), (1)
Host
Rabbit
(30), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(31), (7), (4), (2)
Pubmed 1 reference available
Catalog no. ABIN357707
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ZMPSTE24.
Specificity This antibody is specific to ZMPSTE24 (Center).
Purification Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ZMPSTE24
Background ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alternate names: CAAX prenyl protease 1 homolog, FACE-1, FACE1, Farnesylated proteins-converting enzyme 1, Prenyl protein-specific endoprotease 1, STE24, Zinc metalloproteinase Ste24 homolog
Molecular Weight 54813 Da
Gene ID 10269
NCBI Accession 5874
UniProt O75844
Research Area Proteolysis / Ubiquitin, Cytoskeleton
Application Notes ELISA: 1/1,000. Western Blot: 1/100-1/500. (See Ref.1)Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody
anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody (2) anti-Zinc Metalloproteinase, Ste24 (Zmpste24) (Middle Region) antibody (Image 2)
Background publications Corrigan, Kuszczak, Rusinol et al.: "Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24." in: The Biochemical journal, Vol. 387, Issue Pt 1, pp. 129-38, 2005 (PubMed).

Hosts (30), (5)
Reactivities (31), (10), (8), (3), (1), (1)
Applications (31), (7), (4), (2)
Conjugates (2), (2), (1), (1), (1)
Epitopes (14), (7), (4), (2), (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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