ZMPSTE24 Products
(Zinc Metalloproteinase, Ste24 (Zmpste24))
Categories
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008].
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Featured ZMPSTE24 Categories
ZMPSTE24 Antibodies
High quality antibodies with extensive validation data.
ZMPSTE24 ELISA Kits
Reliable ELISA kits for a wide range of species.
ZMPSTE24 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ZMPSTE24 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7146178
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
- (2)
Cat. No.
ABIN389049
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (2)
Cat. No.
ABIN389048
Quantity
400 μL
Datasheet
Datasheet
Recommended ZMPSTE24 ELISA Kits
Recommended ZMPSTE24 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325830
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325831
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3080077
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ZMPSTE24 products
: "Progeroid syndrome patients with ZMPSTE24 deficiency could benefit when treated with rapamycin and dimethylsulfoxide." in: Cold Spring Harbor molecular case studies, Vol. 3, Issue 1, pp. a001339, (2017) (PubMed).: "LMNA mutations resulting in lipodystrophy and HIV protease inhibitors trigger vascular smooth muscle cell senescence and calcification: Role of ZMPSTE24 downregulation." in: Atherosclerosis, Vol. 245, pp. 200-11, (2016) (PubMed).
: "Membrane proteins of human fetal primitive nucleated red blood cells." in: Journal of proteomics, Vol. 75, Issue 18, pp. 5762-73, (2012) (PubMed).
: "Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 2, pp. 193-201, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
: "HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 33, pp. 13432-7, (2007) (PubMed).
: "A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria." in: Science (New York, N.Y.), Vol. 311, Issue 5767, pp. 1621-3, (2006) (PubMed).
: "Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis." in: Journal of lipid research, Vol. 46, Issue 12, pp. 2531-58, (2005) (PubMed).
: "Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24." in: The Biochemical journal, Vol. 387, Issue Pt 1, pp. 129-38, (2005) (PubMed).
Synonyms and alternative names related to ZMPSTE24
zinc metallopeptidase STE24 (ZMPSTE24), zinc metallopeptidase STE24 L homeolog (zmpste24.L), zinc metallopeptidase STE24 (zmpste24), CAAX prenyl protease (zmpste24), Peptidase family M48 family protein (ATSTE24), zinc metallopeptidase STE24 (Zmpste24), zinc metallopeptidase, STE24 (Zmpste24), zinc metallopeptidase, STE24 homolog (zmpste24), A530043O15Rik, D030046F19, DDBDRAFT_0189115, DDBDRAFT_0237846, DDB_0189115, DDB_0237846, F2N1.21, F2N1_21, FACE-1, Face-1, FACE1, fi45a02, HGPS, MADB, PRO1, STE24, Ste24p, wu:fi45a02, zgc:55655Protein level used designations for ZMPSTE24
- zinc metallopeptidase (STE24 homolog, S. cerevisiae)
- zinc metallopeptidase (STE24 homolog)
- zinc metallopeptidase STE24 homolog
- zinc metalloproteinase STE24 homolog
- CAAX prenyl protease 1 homolog
- STE24 endopeptidase
- zinc metalloproteinase
- zinc metallopeptidase STE24
- CAAX prenyl protease 1 homolog-like
- farnesylated proteins-converting enzyme 1
- prenyl protein-specific endoprotease 1
- zinc metalloproteinase Ste24 homolog
- zinc metallopeptidase, STE24 homolog
- zinc metalloproteinase, STE24 homolog
- farnesylated-proteins converting enzyme 1
- zinc metalloproteinase (STE24 homolog, yeast)
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