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Details for Product No. ABIN357901

Desmin (DES) antibody

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Antigen
Synonyms CSM1, CSM2, LGMD2R, wu:fc11d08, zgc:154009, des-a, MGC52614, DES, des-b, MGC80853, des, csm1, csm2, desm, cmd1i, MGC75911, LOC100220724, desmin, cb290, fb59a12, wu:fb59a12, zgc:109859
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN357901
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T16 of human Desmin.
Specificity This antibody detects Desmin. Predicted to cross react with Mouse (100% Antigen Homology).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Desmin
Background Desmin is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in the gene encoding desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Alternate names: DES
Molecular Weight 53536 Da
Gene ID 1674
NCBI Accession 9606
UniProt P17661
Research Area Cancer, Cytoskeleton
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Li, Lilienbaum, Butler-Browne et al.: "Human desmin-coding gene: complete nucleotide sequence, characterization and regulation of expression during myogenesis and development." in: Gene, Vol. 78, Issue 2, pp. 243-54, 1989 (PubMed).

Ariza, Coll, Fernández-Figueras et al.: "Desmin myopathy: a multisystem disorder involving skeletal, cardiac, and smooth muscle." in: Human pathology, Vol. 26, Issue 9, pp. 1032-7, 1995 (PubMed).

Alternatives for antigen "Desmin (DES)", type "Antibodies"
Hosts (138), (89), (7)
Reactivities (204), (86), (81), (47), (29), (28), (22), (11), (7), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Applications (154), (111), (58), (52), (35), (30), (22), (20), (16), (11), (3), (2), (2), (2), (1), (1)
Conjugates (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1)
Epitopes (23), (13), (12), (12), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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