Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody

Details for Product No. ABIN358008
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Antigen
Synonyms hke2, ke-2, pfd6, h2-ke2, pfdn6a, 23.m05913, H-2Ke2, Ke-2, Pfdn6, H2-KE2, HKE2, KE-2, PFD6, zgc:66282, pfdn6, pfdn6b, Ke2
Epitope
C-Term, N-Term
(7), (2), (1), (1)
Reactivity
Human
(11), (3), (3), (3), (1), (1), (1)
Host
Rabbit
(8), (3)
Clonality
Polyclonal
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(11), (3), (3), (2), (1)
Pubmed 3 references available
Quantity 0.4 mL
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Catalog No. ABIN358008
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PFDN6.
Isotype Ig
Specificity This antibody detects PFDN6 (N-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PFDN6 / HKE2
Background PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.Synonyms: Ke2, PFD6, Prefoldin subunit 6
Molecular Weight 14583 Da
Gene ID 10471, 9606
UniProt O15212
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
anti-Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody anti-Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody
Background publications Vainberg, Lewis, Rommelaere et al.: "Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin." in: Cell, Vol. 93, Issue 5, pp. 863-73, 1998 (PubMed).

Simons, Staes, Rommelaere et al.: "Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4196-203, 2004 (PubMed).

Ostrov, Barnes, Smith et al.: "Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex." in: Tissue antigens, Vol. 69, Issue 2, pp. 181-8, 2007 (PubMed).

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