Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody

Details for Product No. ABIN358008
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Synonyms hke2, ke-2, pfd6, h2-ke2, pfdn6a, 23.m05913, H-2Ke2, Ke-2, Pfdn6, H2-KE2, HKE2, KE-2, PFD6, zgc:66282, pfdn6, pfdn6b, Ke2
C-Term, N-Term
(8), (3), (2), (1)
(15), (5), (5), (4), (1), (1), (1)
(11), (4)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(14), (4), (4), (4), (3)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PFDN6.
Isotype Ig
Specificity This antibody detects PFDN6 (N-term).
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PFDN6 / HKE2 (PFDN6 Antibody Abstract)
Background PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.Synonyms: Ke2, PFD6, Prefoldin subunit 6
Molecular Weight 14583 Da
Gene ID 10471, 9606
UniProt O15212
Application Notes ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Image no. 1 for anti-Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody (ABIN358008) anti-Prefoldin Subunit 6 (PFDN6) (C-Term), (N-Term) antibody
Background publications Ostrov, Barnes, Smith et al.: "Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex." in: Tissue antigens, Vol. 69, Issue 2, pp. 181-8, 2007 (PubMed).

Simons, Staes, Rommelaere et al.: "Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4196-203, 2004 (PubMed).

Vainberg, Lewis, Rommelaere et al.: "Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin." in: Cell, Vol. 93, Issue 5, pp. 863-73, 1998 (PubMed).

Catalog No. ABIN358008
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