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Bardet-Biedl Syndrome 4 (BBS4) (Middle Region) antibody

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Synonyms CG13232, Dmel\\CG13232, zgc:152964, AW537059, AW742241, D9Ertd464e
Middle Region
(12), (8), (7), (5), (4), (4), (4), (2), (2), (2), (1)
(73), (22), (20), (6), (6), (4), (2), (2), (2), (2)
(39), (26), (8)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(62), (25), (11), (4), (3), (3), (2), (2), (1)
Pubmed 3 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human BBS4.
Isotype Ig
Specificity This antibody reacts to BBS4.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name BBS4 (BBS4 Antibody Abstract)
Background BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.Synonyms: Bardet-Biedl syndrome 4 protein
Gene ID 585, 9606
UniProt Q96RK4
Research Area Neurology
Pathways Hedgehog Signaling
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Bardet-Biedl Syndrome 4 (BBS4) (Middle Region) antibody (ABIN359722) Western blot analysis of anti-BBS4 Pab in Hela cell line lysates (35ug/lane).BBS4 (ar...
Background publications Nachury, Loktev, Zhang et al.: "A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis." in: Cell, Vol. 129, Issue 6, pp. 1201-13, 2007 (PubMed).

Ye, Dai, Fang et al.: "Cloning and characterization of a splice variant of human Bardet-Biedl syndrome 4 gene (BBS4)." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 15, Issue 3, pp. 213-8, 2004 (PubMed).

Kim, Badano, Sibold et al.: "The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression." in: Nature genetics, Vol. 36, Issue 5, pp. 462-70, 2004 (PubMed).

Catalog No. ABIN359722
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