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BBS4 antibody (N-Term)

BBS4 Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787344
  • Target See all BBS4 Antibodies
    BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
    Binding Specificity
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 23
    • 18
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Horse, Pig, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig
    Host
    • 26
    • 5
    • 2
    Rabbit
    Clonality
    • 30
    • 3
    Polyclonal
    Conjugate
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BBS4 antibody is un-conjugated
    Application
    • 33
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    YVQALIFRLE GNIQESLELF QTCAVLSPQS ADNLKQVARS LFLLGKHKAA
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against BBS4. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human BBS4
    Top Product
    Discover our top product BBS4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 519 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
    Alternative Name
    BBS4 (BBS4 Products)
    Synonyms
    CG13232 antibody, Dmel\\CG13232 antibody, zgc:152964 antibody, AW537059 antibody, AW742241 antibody, D9Ertd464e antibody, Bardet-Biedl syndrome 4 antibody, bardet-biedl syndrome 4 antibody, Bardet-Biedl syndrome 4 (human) antibody, BBS4 antibody, bbs4 antibody, Bbs4 antibody
    Background
    This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.
    Alias Symbols: -
    Protein Interaction Partner: MYOG, HSCB, FHOD1, EXOC7, EIF3A, PCM1, PAX2, KRT18, EPAS1, EEF1A1, DCTN1, CALCA, BHMT, ALDOB, ACTB, CUL3, UBC,
    Protein Size: 519
    Molecular Weight
    58 kDa
    Gene ID
    585
    NCBI Accession
    NM_033028, NP_149017
    UniProt
    Q96RK4
    Pathways
    Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
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