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Details for Product No. ABIN360481

Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (C-Term) antibody

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Antigen
Synonyms LCCS3, PIP5K-GAMMA, PIP5Kgamma, PIPKIg_v4, AI115456, AI835305, Pip5kIgamma, MGC130766, PIP5K1C, pip5k1a, zgc:110576, si:dkey-29i9.1
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN360481
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PIP5K1G.
Specificity This antibody reacts to PIP5KI gamma.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name PIP5K1C
Background PIP5K1G is a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus.
Alternate names: KIAA0589, PIP5K1-gamma, PIP5KIgamma, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma, PtdIns(4)P-5-kinase 1 gamma
Gene ID 23396
NCBI Accession 9606
UniProt O60331
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Ishihara, Shibasaki, Kizuki et al.: "Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8741-8, 1998 (PubMed).

Di Paolo, Pellegrini, Letinic et al.: "Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin." in: Nature, Vol. 420, Issue 6911, pp. 85-9, 2002 (PubMed).

Ling, Doughman, Firestone et al.: "Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions." in: Nature, Vol. 420, Issue 6911, pp. 89-93, 2002 (PubMed).

Alternatives for antigen "Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C)", type "Antibodies"
Hosts (19), (3)
Reactivities (22)
Applications (22), (15), (5), (2), (1), (1)
Epitopes (5), (2), (2), (2), (2)
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