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Details for Product No. ABIN360481

Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (C-Term) antibody

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Antigen
Synonyms LCCS3, PIP5K-GAMMA, PIP5Kgamma, PIPKIg_v4, AI115456, AI835305, Pip5kIgamma, MGC130766, PIP5K1C, pip5k1a, zgc:110576, si:dkey-29i9.1
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN360481
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (C-Term) antibody

anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (C-Term) antibody (2)

Product details

Target Details Application Details Handling Images References Alternatives back to top
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PIP5K1G.
Specificity This antibody reacts to PIP5KI gamma.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Target Details

Application Details Handling Images References Alternatives back to top
Alternative Name PIP5K1C
Background PIP5K1G is a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus.
Alternate names: KIAA0589, PIP5K1-gamma, PIP5KIgamma, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma, PtdIns(4)P-5-kinase 1 gamma
Gene ID 23396
NCBI Accession 9606
UniProt O60331

Application Details

Target Details Handling Images References Alternatives back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Target Details Application Details Images References Alternatives back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months

References

Target Details Application Details Handling Images Alternatives back to top
Background publications Ishihara, Shibasaki, Kizuki et al.: "Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8741-8, 1998 (PubMed).

Di Paolo, Pellegrini, Letinic et al.: "Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin." in: Nature, Vol. 420, Issue 6911, pp. 85-9, 2002 (PubMed).

Ling, Doughman, Firestone et al.: "Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions." in: Nature, Vol. 420, Issue 6911, pp. 89-93, 2002 (PubMed).

Alternatives

Target Details Application Details Handling Images References back to top
Alternatives for antigen "Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C)", type "Antibodies"
Hosts (19), (3)
Reactivities (22)
Applications (22), (15), (5), (2), (1), (1)
Epitopes (5), (2), (2), (2), (2)
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