Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (C-Term) antibody

Details for Product No. ABIN360704
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Antigen
Synonyms CNKSR3, AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, TNRC19, WWP3, Baiap1, Gukmi1, MAGI1c, Magi-1, mKIAA4129
Epitope
C-Term
(7), (7), (3), (1), (1), (1), (1)
Reactivity
Human
(30), (4), (4)
Host
Rabbit
(16), (14)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (2), (2), (2), (2), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(29), (19), (6), (6), (2), (2), (1)
Pubmed 5 references available
Quantity 0.4 mL
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Catalog No. ABIN360704
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Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BAIAP1.
Specificity This antibody reacts to BAIAP1.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Alternative Name MAGI1 / BAIAP1
Background BAIAP1 is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. Characterized by two WW domains, a guanylate kinase domain, and five PDZ domains, this protein interacts with the cytoplasmic region of BAI1. Together, these proteins may play a role in cell adhesion and signal transduction.
Alternate names: AIP-3, AIP3, Atrophin-1-interacting protein 3, BAI1-associated protein 1, BAP-1, BAP1, MAGI-1, MAGI-1, Membrane-associated guanylate kinase, Membrane-associated guanylate kinase inverted 1, TNRC19, Trinucleotide repeat-containing gene 19 protein, WW and PDZ domain-containing protein 1, WWP3
Gene ID 9223
NCBI Accession NP_001028229
UniProt Q96QZ7
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (C-Term) antibody anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (C-Term) antibody
anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (C-Term) antibody (2) anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (C-Term) antibody (Image 2)
Background publications Pirozzi, McConnell, Uveges et al.: "Identification of novel human WW domain-containing proteins by cloning of ligand targets." in: The Journal of biological chemistry, Vol. 272, Issue 23, pp. 14611-6, 1997 (PubMed).

Margolis, Abraham, Gatchell et al.: "cDNAs with long CAG trinucleotide repeats from human brain." in: Human genetics, Vol. 100, Issue 1, pp. 114-22, 1997 (PubMed).

Wood, Yuan, Margolis et al.: "Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins." in: Molecular and cellular neurosciences, Vol. 11, Issue 3, pp. 149-60, 1998 (PubMed).

Shiratsuchi, Futamura, Oda et al.: "Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1." in: Biochemical and biophysical research communications, Vol. 247, Issue 3, pp. 597-604, 1998 (PubMed).

Patrie, Drescher, Welihinda et al.: "Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 30183-90, 2002 (PubMed).

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