GRP78 antibody (C-Term)
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- Target See all GRP78 (HSPA5) Antibodies
- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
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Binding Specificity
- AA 600-654, C-Term
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Reactivity
- Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GRP78 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Reacts with rat and mouse 78 kDa GRP-78 protein
- Cross-Reactivity (Details)
- Weakly cross reacts with human GRP-78.
- Purification
- Antigen affinity purified
- Immunogen
- Synthetic peptide derived from C-term domain of the rat Grp78 protein. Within residues 600-654.
- Top Product
- Discover our top product HSPA5 Primary Antibody
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anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody
HSPA5 Reactivity: Human, Mouse WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB1768 unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibodyHSPA5 Reactivity: Rat WB, IHC, IF, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (Internal Region) antibodyHSPA5 Reactivity: Human, Rat, Mouse WB, IF, ICC, IP, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 550-650) antibodyHSPA5 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) (AA 251-360) antibodyHSPA5 Reactivity: Human, Rat, Mouse WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (HRP)HSPA5 Reactivity: Rat WB, IHC, IF, ICC, IP Host: Rabbit Polyclonal HRP
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (FITC)HSPA5 Reactivity: Rat WB, IHC, IF, ICC, IP Host: Rabbit Polyclonal FITC
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (Biotin)HSPA5 Reactivity: Rat WB, IHC, IF, ICC, IP Host: Rabbit Polyclonal Biotin
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (PE)HSPA5 Reactivity: Rat WB, IHC, IF, ICC, IP Host: Rabbit Polyclonal PE
anti-Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5) antibody (APC)HSPA5 Reactivity: Rat WB, IHC, IF, ICC, IP Host: Rabbit Polyclonal APC
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB0.5 μg/mL ICC/IF1:50 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.05 mg/mL
- Buffer
- PBS, glycerol 30 % , Sodium azide 0.1 %
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 6 months
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- Target
- GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
- Alternative Name
- 78 kDa Glucose-Regulated Protein (GRP-78) (HSPA5 Products)
- Background
- Categorized as stress response proteins, BiPs play an important role in folding and assembly of nascent proteins and in scavenging of misfolded proteins in the endoplasmic reticulum lumen. Translation of BiP is directed by an internal ribosomal entry site (IRES) in the 5- nontranslated region of BiP mRNA. BiP IRES activity increases when cells are heat-stressed. GRP78 is also important in maintenance of cell homeostasis and the prevention of apoptosis. Levels of GRP78 protein are reduced in brains of Alzheimer's disease patients.
- Gene ID
- 25617
- Pathways
- Thyroid Hormone Synthesis, ER-Nucleus Signaling
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