HSPA5
Reactivity: Rat
WB, IHC, IF, ICC, IP
Host: Rabbit
Polyclonal
PerCP
Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Abdullah, Ravanan: "Kaempferol mitigates Endoplasmic Reticulum Stress Induced Cell Death by targeting caspase 3/7." in: Scientific reports, Vol. 8, Issue 1, pp. 2189, (2018) (PubMed).
Jiang, He, Zhu, Liang, Wang, Lu, Ren, Yi, Xiao, Wang: "Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model." in: Experimental cell research, Vol. 369, Issue 2, pp. 325-334, (2018) (PubMed).
Anasa, Manickam, Talwar, Ravanan: "Identification of ASB7 as ER stress responsive gene through a genome wide in silico screening for genes with ERSE." in: PLoS ONE, Vol. 13, Issue 4, pp. e0194310, (2018) (PubMed).
Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).
Wang, Zhu, Li, Yang, Xiao, Kang, Li, Zhao, Zeng, Li, Zhang, He, Ying et al.: "Crude Saponins of Panax notoginseng Have Neuroprotective Effects To Inhibit Palmitate-Triggered Endoplasmic Reticulum Stress-Associated Apoptosis and Loss of Postsynaptic Proteins in Staurosporine ..." in: Journal of agricultural and food chemistry, Vol. 64, Issue 7, pp. 1528-39, (2016) (PubMed).
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Background
The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.,HSPA5,BIP,GRP78,HEL-S-89n,MIF2,Neuroscience,Neurodegenerative Diseases,HSPA5