For best experience we recommend to activate Javascript in your browser.

CD38 antibody

Reactivity: Mouse FACS, IP, IHC (fro), Func Host: Rat Monoclonal NIMR-5 unconjugated

Catalog No. ABIN370933

Datasheet as PDF

Target See all CD38 Antibodies

CD38
Reactivity
157

62

22

12

12

12

1

1
Mouse
Host
93

89

27

1

1

1
Rat
Compatible Secondaries
Clonality
135

75

1
Monoclonal
Conjugate
68

15

13

12

10

5

5

4

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
This CD38 antibody is un-conjugated
Application
152

66

41

33

32

26

26

20

18

17

10

7

3

2

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Specificity

This antibody is specific to CD38 (Mr. 42-46 kDa). Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis. (Ref.1-8)

Characteristics

Synonyms: cADPr hydrolase 1, T10, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1

Purification

Purified

Clone

NIMR-5

Isotype

IgG2a

Top Product

Discover our top product CD38 Primary Antibody
anti-CD38 (AA 241-270), (C-Term) antibody
Reactivity: Human FACS, WB, IF, IHC (p) Host: Rabbit Polyclonal RB18001 unconjugated

anti-CD38 (AA 1-300) antibody
Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-CD38 (AA 43-300) antibody
Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 5C5C3 unconjugated

anti-CD38 (AA 46-300) antibody
Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-CD38 (AA 241-270) antibody
Reactivity: Human FACS, WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-CD38 antibody
Reactivity: Human FACS, WB, IHC (fro), IHC (p) Host: Mouse Monoclonal HIT2 unconjugated

anti-CD38 (Internal Region) antibody
Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-CD38 antibody (APC)
Reactivity: Human FACS Host: Mouse Monoclonal HIT2 APC

anti-CD38 antibody (PE)
Reactivity: Human FACS Host: Mouse Monoclonal HIT2 PE

anti-CD38 antibody (Biotin)
GMP Grade Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal OKT10 Biotin

Application Notes

Flow Cytometry. (Ref.1-8)Immunoprecipitation. Immunohistochemistry on Frozen Sections. (Ref.7)Functional Assay: Induction of B lymphocyte proliferation. (Ref.3-8)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date

12 months
Target

CD38

Abstract

CD38 Products

Background

Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing Nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRalphabeta+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1

Gene ID

12494

UniProt

P56528