Keratin 19 (KRT19) (C-Term) antibody

Details for Product No. ABIN371616
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

 
Antigen
Synonyms CK19, K19, K1CS, AI663979, EndoC, Krt-1.19, Krt1-19, Ka19, GK-19, k19, ck19, k1cs, krt9, krt15, MGC76282, MGC83069, KRT19, MGC154386, DKFZp469N0613
Epitope
C-Term
(31), (8), (8), (6), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Please enquire
(288), (59), (50), (18), (17), (16), (13), (7), (4), (3), (2), (1), (1), (1)
Host
Mouse
(181), (125), (4), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(12), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Western Blotting (WB)
(223), (150), (117), (95), (65), (59), (55), (31), (17), (10), (6), (4), (3), (2), (1)
Pubmed 8 references available
Catalog no. ABIN371616
Quantity 0.1 mg
Price
286.00 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Recombinant C-terminal keratin 19.
Clone SB39g
Isotype IgG2a
Characteristics Synonyms: Cytokeratin-19, Keratin-19, KRT19, CK19, K19, Keratin type I cytoskeletal 19
Purification Purified
Alternative Name Cytokeratin 19
Background Keratins are a family of intermediate filament proteins that assemble into filamentsthrough forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin(keratins 1-8). The two keratin types share only 30% sequence homology. (Ref. 1-5) Keratinsdemonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 19 is thesmallest human keratin, is found in many simple and some non-keratinizing stratifiedsquamous epithelia, and is often co-expressed with keratin 7. (Ref. 6,7) Cytokeratin 19 hasbeen implicated as a marker for stem cells in some tissues, such as hair follicles in theskin.
UniProt P08727
Research Area Signaling, Cytoskeleton, Cytokeratins, Extracellular Matrix
Application Notes ELISA. Western Blot: 1/2,000-1/4,000. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections): 10 µg/mlOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer 100 mM Borate buffered saline, pH 8.0 without preservatives or amine-containing buffer salts.
Preservative Without preservative
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Keratin 19 (KRT19) (C-Term) antibody anti-Keratin 19 (KRT19) (C-Term) antibody
Background publications Bosch, Leube, Achtstätter et al.: "Expression of simple epithelial type cytokeratins in stratified epithelia as detected by immunolocalization and hybridization in situ." in: The Journal of cell biology, Vol. 106, Issue 5, pp. 1635-48, 1988 (PubMed).

Fuchs, Coppock, Green et al.: "Two distinct classes of keratin genes and their evolutionary significance." in: Cell, Vol. 27, Issue 1 Pt 2, pp. 75-84, 1982 (PubMed).

Tseng, Jarvinen, Nelson et al.: "Correlation of specific keratins with different types of epithelial differentiation: monoclonal antibody studies." in: Cell, Vol. 30, Issue 2, pp. 361-72, 1983 (PubMed).

Moll, Franke, Schiller et al.: "The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells." in: Cell, Vol. 31, Issue 1, pp. 11-24, 1983 (PubMed).

Hanukoglu, Fuchs: "The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins." in: Cell, Vol. 33, Issue 3, pp. 915-24, 1983 (PubMed).

Franke, Schiller, Hatzfeld et al.: "Protein complexes of intermediate-sized filaments: melting of cytokeratin complexes in urea reveals different polypeptide separation characteristics." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 80, Issue 23, pp. 7113-7, 1984 (PubMed).

Schiller, Franke, Geiger: "A subfamily of relatively large and basic cytokeratin polypeptides as defined by peptide mapping is represented by one or several polypeptides in epithelial cells." in: The EMBO journal, Vol. 1, Issue 6, pp. 761-9, 1984 (PubMed).

Wu, Nishioka, Fujita et al.: "Expression of cytokeratin 19 in human hepatocellular carcinoma cell lines." in: International journal of oncology, Vol. 20, Issue 1, pp. 31-7, 2001 (PubMed).

Hosts (181), (125), (4), (2), (1)
Reactivities (288), (59), (50), (18), (17), (16), (13), (7), (4), (3), (2), (1), (1), (1)
Applications (223), (150), (117), (95), (65), (59), (55), (31), (17), (10), (6), (4), (3), (2), (1)
Conjugates (12), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (31), (8), (8), (6), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
back to top