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PPP2R5E antibody (Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform) (C-Term)

Details for Product anti-PPP2R5E Antibody No. ABIN374131, Supplier: Login to see New
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Synonyms wdb2, ppp2r5e, ppp2r5e1, PPP2R5E, 4633401M22Rik, AI449017, B56beta
(14), (6), (3), (1), (1), (1), (1)
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(17), (16), (2), (2), (1), (1), (1)
(16), (12), (1)
This PPP2R5E antibody is un-conjugated
(1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(25), (16), (3)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
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Immunogen Peptide from C Terminus of the protein sequence according to NP_006237.1 Genename: PPP2R5E
Specificity This antibody detects PPP2R5E at C-term.
Cross-Reactivity (Details) Species reactivity (expected):Human, Rat, Dog and Cow.
Species reactivity (tested):Mouse.
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Alternative Name PPP2R5E (PPP2R5E Antibody Abstract)
Background The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily.Synonyms: PP2A B subunit B'epsilon isoform, PP2A B subunit B56 epsilon isoform, PP2A B subunit PR61 epsilon isoform, PP2A B subunit R5 epsilon isoform, Protein phosphatase 2A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
Gene ID 5529
NCBI Accession NP_006237
UniProt Q16537
Research Area Signaling
Pathways PI3K-Akt Signaling
Application Notes Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 μg/mL. Approx 55 kDa and 45 kDa bands seen in mouse brain extracts. Please note that the two bands may correspond to two different isoforms. Two isoforms ofthe epsilon mRNA have been detected in Northern blots (J Biol Chem 1996 Sep6,271(36): 22081-9).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
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 image for anti-PPP2R5E antibody (Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform) (C-Term) (ABIN374131) anti-Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform (PPP2R5E) (C-Term) antibody
Background publications McCright, Virshup: "Identification of a new family of protein phosphatase 2A regulatory subunits." in: The Journal of biological chemistry, Vol. 270, Issue 44, pp. 26123-8, 1995 (PubMed).

Catalog No. ABIN374131
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