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Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform (PPP2R5E) (C-Term) antibody

Details for Product No. ABIN374131
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Antigen
Synonyms wdb2, ppp2r5e, ppp2r5e1, PPP2R5E, 4633401M22Rik, AI449017, B56beta
Epitope
C-Term
(4), (3), (2), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(11), (4), (1)
Host
Goat
(8), (6), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(13), (4), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN374131
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Immunogen Peptide from C Terminus of the protein sequence according to NP_006237.1 Genename: PPP2R5E
Sequence C-LKRGLRRDGIIPT
Specificity This antibody detects PPP2R5E at C-term.
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Alternative Name PPP2R5E
Background The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily.
Alternate names: PP2A B subunit B'epsilon isoform, PP2A B subunit B56 epsilon isoform, PP2A B subunit PR61 epsilon isoform, PP2A B subunit R5 epsilon isoform, Protein phosphatase 2A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
Gene ID 5529
NCBI Accession NP_006237.1
UniProt Q16537
Research Area Signaling
Application Notes Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.5-2 µg/ml. Approx 55kDa and 40kDa bands seen in mouse brain extracts. Please note that the two bands may correspond to two different isoforms. Two isoforms ofthe epsilon mRNA have been detected in Northern blots (J Biol Chem 1996 Sep6,271(36): 22081-9). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, pH~7.3 0.02% Sodium Azide 0.5% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C.
Expiry Date 12 months
Supplier Images
anti-Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform (PPP2R5E) (C-Term) antibody anti-Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform (PPP2R5E) (C-Term) antibody
Background publications McCright, Virshup: "Identification of a new family of protein phosphatase 2A regulatory subunits." in: The Journal of biological chemistry, Vol. 270, Issue 44, pp. 26123-8, 1995 (PubMed).

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