P-Selectin antibody (SPRD)

Catalog No. ABIN375582

Product Details anti-P-Selectin Antibody (SPRD)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This P-Selectin antibody is conjugated to SPRD

Application: Flow Cytometry (FACS)

Brand: Spectral Red ™

Specificity: Human CD62E & CD62P/Porcine CD62E, Mr 97 kDa/140 kDa

Characteristics: Mouse Anti-Human CD62E/CD62P-SPRD

Purification: Purified

Immunogen: TNF stimulated human endothelial cells

Clone: 1-2B6

Isotype: IgG1

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB-NR - Reported in literature , ELISA - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, SPRD, and AF700 conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Comment:

Inhibition of activity

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: The purified (UNLB) antibody is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added.

Preservative: Without preservative

Handling Advice: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Alternative Name: CD62E/CD62P (SELP Products)

Background: E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues.