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K(lysine) Acetyltransferase 2A (KAT2A) (N-Term), (AA 65-94) antibody

Details for Product No. ABIN387930
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Antigen
Synonyms KAT2A, GCN5L2, GCN5, PCAF-b, hGCN5, 1110051E14Rik, AW212720, Gcn5, Gcn5l2, mmGCN5
Epitope
N-Term, AA 65-94
(13), (8), (8), (8), (6), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(69), (13), (3)
Host
Rabbit
(41), (29)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(62), (42), (11), (10), (5), (3), (2), (2)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN387930
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Immunogen This GCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 AA from the N-terminal region of human GCN5.
Clone RB14374
Isotype Ig
Specificity This GCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72~102 amino acids from the N-term region of human GCN5.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name GCN5
Background GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. This protein has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles.
Synonyms: GCN5 general control of amino-acid synthesis 5-like 2, Yeast, GCN5L2
Molecular Weight 93836 DA
Gene ID 2648
UniProt Q8N1A2
Research Area Signaling, Protein Modifications, Transcription Factors, Chromatin
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-K(lysine) Acetyltransferase 2A (KAT2A) (N-Term), (AA 65-94) antibody Western blot analysis of anti-GCN5 Antibody (N-term)(ABIN387930) in 293 cell line lysates (35 µg/lane). GCN5(arrow) was detected using the purified polyclonal antibody (1:60 dilution).
Background publications Oishi, Kitagawa, Wada et al.: "An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification." in: The Journal of biological chemistry, Vol. 281, Issue 1, pp. 20-6, 2006 (PubMed).

Wiper-Bergeron, Salem, Tomlinson et al.: "Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 8, pp. 2703-8, 2007 (PubMed).

Validation Images
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