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HAT1 antibody (C-Term)

HAT1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB5769 unconjugated
Catalog No. ABIN387932
  • Target See all HAT1 Antibodies
    HAT1 (Histone Acetyltransferase 1 (HAT1))
    Binding Specificity
    • 10
    • 10
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 389-419, C-Term
    Reactivity
    • 64
    • 18
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 63
    • 2
    Rabbit
    Clonality
    • 62
    • 3
    Polyclonal
    Conjugate
    • 29
    • 7
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HAT1 antibody is un-conjugated
    Application
    • 54
    • 42
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This KAT1 (HAT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the C-terminal region of human KAT1 (HAT1).
    Clone
    RB5769
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HAT1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:100. IHC-P: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    HAT1 (Histone Acetyltransferase 1 (HAT1))
    Alternative Name
    KAT1 (HAT1) (HAT1 Products)
    Synonyms
    KAT1 antibody, HAC07 antibody, HAC7 antibody, HAG02 antibody, MIK19.19 antibody, MIK19_19 antibody, histone acetyltransferase of the GNAT family 2 antibody, hac106 antibody, hat1 antibody, zgc:92639 antibody, histone acetyltransferase 1 antibody, histone acetyltransferase of the GNAT family 2 antibody, histone acetyltransferase catalytic subunit antibody, histone acetyltransferase Hat1 antibody, histone acetyltransferase 1 L homeolog antibody, HAT1 antibody, Hat1 antibody, HAG2 antibody, hat1 antibody, hat1.L antibody
    Background
    Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.
    Molecular Weight
    49513
    Gene ID
    8520
    NCBI Accession
    NP_003633
    UniProt
    O14929
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