HAT1 antibody
Quick Overview for HAT1 antibody (ABIN7267702)
Target
See all HAT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- KAT1/HAT1 Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human KAT1/HAT1
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- HAT1 (Histone Acetyltransferase 1 (HAT1))
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Alternative Name
- HAT1
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Background
- The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009],KAT1,Cell Biology & Developmental Biology,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Acetylation,Epigenetics & Nuclear Signaling,Notch Signaling Pathway,HAT1
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Molecular Weight
- 45kDa
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Gene ID
- 8520
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UniProt
- O14929
Target
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