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Details for Product No. ABIN388052

SUMO1/sentrin Specific Protease 6 (SENP6) (C-Term), (AA 1081-1112) antibody

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Antigen
Synonyms SSP1, SUSP1
Epitope
»Alternatives C-Term, AA 1081-1112
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN388052
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This SENP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1081-1112 AA from the C-terminal region of human SENP6.
Clone RB0664
Isotype Ig
Specificity This SENP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1083~1112 amino acids from the C-terminal region of human SENP6.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name SENP6
Background SENP6 (SUSP1) is a protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. This protein does not seem to be involved in the processing of full-length SUMO proteins to their mature conjugatable forms. SENP6 deconjugates SUMO1 from RXRA, leading to transcriptional activation. It may act preferentially on substrates containing 3 or more SUMO2 or SUMO3 moieties.
Synonyms: Sentrin-specific protease 6, Sentrin/SUMO-specific protease SENP6, SUMO-1-specific protease 1, SENP6, KIAA0797, SSP1, SUSP1
Molecular Weight 126144 DA
Gene ID 26054
UniProt Q9GZR1
Research Area Apoptosis/Necrosis, Cell Signaling, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Kim, Baek, Jeon et al.: "A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs." in: The Journal of biological chemistry, Vol. 275, Issue 19, pp. 14102-6, 2000 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Alternatives for antigen "SUMO1/sentrin Specific Protease 6 (SENP6)", type "Antibodies"
Hosts (27), (12), (4)
Reactivities (40), (6), (2), (2)
Applications (30), (24), (11), (7), (1)
Epitopes (8), (3), (2), (2), (2), (2), (1), (1)
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