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Details for Product No. ABIN388102

Bcl2 Modifying Factor (BMF) (AA 115-150), (BH3 Domain) antibody

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Antigen
Synonyms AW260063, AW411872, BMF
Epitope
»Alternatives AA 115-150, BH3 Domain
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN388102
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This Bmf BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-150 AA from human Bmf BH3 Domain.
Clone RB00594
Isotype Ig
Specificity This Bmf BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124~153 amino acids from aa 130-150 of human Bmf.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Bmf
Background Bmf belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis.
Synonyms: Bcl-2 Modifying Factor
Molecular Weight 20682 DA
Gene ID 90427
UniProt Q96LC9
Research Area Apoptosis/Necrosis, Cancer, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Puthalakath, Villunger, OReilly et al.: "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." in: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1829-32, 2001 (PubMed).

Alternatives for antigen "Bcl2 Modifying Factor (BMF)", type "Antibodies"
Hosts (57), (5), (2), (1)
Reactivities (60), (27), (15), (11), (11)
Applications (53), (23), (12), (11), (9), (9), (7), (7), (5), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (15), (11), (3), (3), (1), (1), (1), (1), (1)
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