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Details for Product No. ABIN389186

Cadherin 5 (CDH5) (N-Term), (AA 106-134) antibody

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Antigen
Synonyms 7B4, CD144, AA408225, Cd144, VE-Cad, VECD, VEcad, Vec, cadherin-5, wu:fc88a07
Epitope
»Alternatives N-Term, AA 106-134
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN389186
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This VE Cadherin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 AA from the N-terminal region of human VE Cadherin.
Clone RB13659
Isotype Ig
Specificity This CDH5 (N-term) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113~142 amino acids from the N-term of human CDH5.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VE Cadherin (CDH5)
Background CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
Synonyms: Cadherin-5,Vascular endothelial cadherin,VE-cadherin,7B4 antigen,CD144 antigen,CDH5
Molecular Weight 87516 DA
Gene ID 1003
UniProt P33151
Research Area Cell Structure, Cancer
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.43 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Breviario, Caveda, Corada et al.: "Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 15, Issue 8, pp. 1229-39, 1995 (PubMed).

Alternatives for antigen "Cadherin 5 (CDH5)", type "Antibodies"
Hosts (85), (32), (14), (1)
Reactivities (96), (74), (46), (29), (19), (1), (1)
Applications (82), (82), (49), (20), (20), (18), (14), (12), (12), (8), (6), (6), (5), (4), (1), (1), (1), (1)
Conjugates (13), (9), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (10), (10), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1)
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