Cadherin 5 Products
(Cadherin 5 (CDH5))
Categories
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
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Featured Cadherin 5 Categories
Cadherin 5 Antibodies
High quality antibodies with extensive validation data.
Cadherin 5 ELISA Kits
Reliable ELISA kits for a wide range of species.
Cadherin 5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cadherin 5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, ICC, IHC (p), IHC (fro), IF (p), IF (cc)
Validations
- (6)
Cat. No.
ABIN729343
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7433546
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, FACS
Validations
- (2)
- (4)
Cat. No.
ABIN1724747
Quantity
100 μL
Datasheet
Datasheet
Recommended Cadherin 5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6954248
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6963680
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965299
Quantity
96 tests
Datasheet
Datasheet
Recommended Cadherin 5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (3)
Cat. No.
ABIN3090342
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348918
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320374
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Cadherin 5 products
: "aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability." in: Nature communications, Vol. 9, Issue 1, pp. 5357, (2019) (PubMed).: "Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 50, pp. 12817-12822, (2019) (PubMed).
: "Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis." in: Nature communications, Vol. 10, Issue 1, pp. 1929, (2019) (PubMed).
: "Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis." in: Cancer discovery, Vol. 9, Issue 1, pp. 82-95, (2019) (PubMed).
: "Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling." in: Scientific reports, Vol. 9, Issue 1, pp. 13591, (2019) (PubMed).
: "Hsp90β promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma." in: Oncogene, (2018) (PubMed).
: "Application of multifunctional targeting epirubicin liposomes in the treatment of non-small-cell lung cancer." in: International journal of nanomedicine, Vol. 12, pp. 7433-7451, (2018) (PubMed).
: "Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells." in: Journal of tissue engineering and regenerative medicine, Vol. 11, Issue 11, pp. 3241-3252, (2018) (PubMed).
: "Vascular CXCR4 Expression Promotes Vessel Sprouting and Sensitivity to Sorafenib Treatment in Hepatocellular Carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 15, pp. 4482-4492, (2018) (PubMed).
: "The Superantigen Toxic Shock Syndrome Toxin-1 Alters Human Aortic Endothelial Cell Function." in: Infection and immunity, (2018) (PubMed).
Synonyms and alternative names related to Cadherin 5
cadherin 5 (CDH5), cadherin 5 (Cdh5), cadherin 5 (cdh5), 7B4, AA408225, cadherin-5, Cd144, CD144, VE-Cad, Vec, VEcad, VECD, wu:fc88a07Protein level used designations for Cadherin 5
- cadherin 5, type 2, VE-cadherin (vascular endothelium)
- cadherin 5, type 2, VE-cadherin (vascular epithelium)
- 7B4/cadherin-5
- VE-cadherin
- cadherin-5
- vascular endothelial cadherin
- VE-cadherin (vascular epithelium)
- fc88a07
- type 2
- vecdn
- 7B4 antigen
- cd144 antigen
- endothelial-specific cadherin
- VE cadherin
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