Exosome Component 8 (EXOSC8) (C-Term), (AA 243-276) antibody

Details for Product No. ABIN389276
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Synonyms p9, CIP3, EAP2, OIP2, RRP43, Rrp43p, bA421P11.3, RP11-421P11.3, 2310032N20Rik, mKIAA4013, wu:fb79a10, zgc:110381, MGC52847, MGC132146, EXOSC8, MGC79733
C-Term, AA 243-276
(3), (1)
(13), (3), (3)
(7), (6)
Clonality (Clone)
Polyclonal ()
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(9), (4), (4), (3), (2), (2), (2)
Pubmed 1 reference available
Catalog no. ABIN389276
Quantity 400 µL
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Immunogen This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-276 AA from the C-terminal region of human EXOSC8.
Clone RB17686
Isotype Ig
Specificity This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247~276 amino acids from the C-terminal region of human EXOSC8.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EXOSC8
Background EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.
Synonyms: Exosome complex exonuclease RRP43, Ribosomal RNA-processing protein 43, Exosome component 8, p9, Opa-interacting protein 2, EXOSC8, OIP2, RRP43
Molecular Weight 29909 DA
Gene ID 11340
UniProt Q96B26
Research Area Translation Factors, Stem Cells, Signaling
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Exosome Component 8 (EXOSC8) (C-Term), (AA 243-276) antibody Western blot analysis of anti-EXOSC8 Antibody (C-term) (ABIN389276) in HL60 cell line lysates (35 µg/lane). EXOSC8(arrow) was detected using the purified polyclonal antibody.
anti-Exosome Component 8 (EXOSC8) (C-Term), (AA 243-276) antibody (2) Formalin-fixed and paraffin-embedded human brain tissue with EXOSC8 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Exosome Component 8 (EXOSC8) (C-Term), (AA 243-276) antibody (3) EXOSC8 Antibody (C-term) (ABIN389276) flow cytometry analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Jiang, Altman: "A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 8, pp. 5295-300, 2002 (PubMed).

Hosts (7), (6)
Reactivities (13), (3), (3)
Applications (9), (4), (4), (3), (2), (2), (2)
Epitopes (3), (1)
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