Exosome Component 8 (EXOSC8) (C-Term), (AA 243-276) antibody

Details for Product No. ABIN389276
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Antigen
Synonyms p9, CIP3, EAP2, OIP2, RRP43, Rrp43p, bA421P11.3, RP11-421P11.3, 2310032N20Rik, mKIAA4013, wu:fb79a10, zgc:110381, MGC52847, MGC132146, EXOSC8, MGC79733
Epitope
C-Term, AA 243-276
(3), (1)
Reactivity
Human
(13), (3), (3)
Host
Rabbit
(7), (6)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(9), (4), (4), (3), (2), (2), (2)
Pubmed 1 reference available
Catalog no. ABIN389276
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-276 AA from the C-terminal region of human EXOSC8.
Clone RB17686
Isotype Ig
Specificity This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247~276 amino acids from the C-terminal region of human EXOSC8.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EXOSC8
Background EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.
Synonyms: Exosome complex exonuclease RRP43, Ribosomal RNA-processing protein 43, Exosome component 8, p9, Opa-interacting protein 2, EXOSC8, OIP2, RRP43
Molecular Weight 29909 DA
Gene ID 11340
UniProt Q96B26
Research Area Translation Factors, Stem Cells, Signaling
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Exosome Component 8 (EXOSC8) (C-Term), (AA 243-276) antibody Western blot analysis of anti-EXOSC8 Antibody (C-term) (ABIN389276) in HL60 cell line lysates (35 µg/lane). EXOSC8(arrow) was detected using the purified polyclonal antibody.
anti-Exosome Component 8 (EXOSC8) (C-Term), (AA 243-276) antibody (2) Formalin-fixed and paraffin-embedded human brain tissue with EXOSC8 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Exosome Component 8 (EXOSC8) (C-Term), (AA 243-276) antibody (3) EXOSC8 Antibody (C-term) (ABIN389276) flow cytometry analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Jiang, Altman: "A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 8, pp. 5295-300, 2002 (PubMed).

Hosts (7), (6)
Reactivities (13), (3), (3)
Applications (9), (4), (4), (3), (2), (2), (2)
Epitopes (3), (1)
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