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Details for Product No. ABIN390140

Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16) (N-Term), (AA 154-183) antibody

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Antigen
Synonyms Mt3mmp, MT3-MMP, Mt3-mmp, C8orf57, MMP-X2, MT-MMP2, MT-MMP3
Epitope
»Alternatives N-Term, AA 154-183
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN390140
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 AA from the N-terminal region of human MMP16.
Clone RB2031
Isotype Ig
Specificity This MMP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MMP16.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MMP16
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene for MMP16 produces two transcripts, which encode a membrane-bound form and a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
Synonyms: MMP16
Molecular Weight 53kd Isoform. 69521 DA
Gene ID 4325
UniProt NP_072086
Research Area Stem Cells, Cell Structure, Protein Modifications, Cancer
Application Notes Recommend dilutions: IHC : 1:50-100,WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Mattei, Roeckel, Olsen et al.: "Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively." in: Genomics, Vol. 40, Issue 1, pp. 168-9, 1997 (PubMed).

Sato, Tanaka, Takino et al.: "Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization." in: Genomics, Vol. 39, Issue 3, pp. 412-3, 1997 (PubMed).

Matsumoto, Katoh, Saito et al.: "Identification of soluble type of membrane-type matrix metalloproteinase-3 formed by alternatively spliced mRNA." in: Biochimica et biophysica acta, Vol. 1354, Issue 2, pp. 159-70, 1998 (PubMed).

Alternatives for antigen "Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16)", type "Antibodies"
Hosts (66), (1), (1)
Reactivities (65), (37), (32), (18), (18), (17), (17), (1), (1)
Applications (41), (25), (15), (15), (15), (12), (10), (4), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
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