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MMP16 Products

(Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010].

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Featured MMP16 Categories

MMP16 Antibodies

High quality antibodies with extensive validation data.

MMP16 ELISA Kits

Reliable ELISA kits for a wide range of species.

MMP16 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MMP16 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN6143906
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7255303
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (2)
  • (5)
Cat. No. ABIN5519039
Quantity 100 μg
Datasheet Datasheet

Recommended MMP16 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957690
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381328
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951672
Quantity 96 tests
Datasheet Datasheet

Recommended MMP16 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083683
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3120007
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3113813
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MMP16 products

Wu, Ma, Shan, Zhou, Li: "High expression of matrix metalloproteinases 16 is associated with the aggressive malignant behavior and poor survival outcome in colorectal carcinoma." in: Scientific reports, Vol. 7, pp. 46531, (2017) (PubMed).

Shen, Wang, Yu, Zhang, Qin: "MMP16 promotes tumor metastasis and indicates poor prognosis in hepatocellular carcinoma." in: Oncotarget, Vol. 8, Issue 42, pp. 72197-72204, (2017) (PubMed).

Xue, Wu, Chen, Luo: "MT3-MMP down-regulation promotes tumorigenesis and correlates to poor prognosis in esophageal squamous cell carcinoma." in: Cancer medicine, Vol. 5, Issue 9, pp. 2459-68, (2017) (PubMed).

Meng, Tong, Liu, Yu, Zhang, Gao: "Epigallocatechin-3-gallate inhibits growth and induces apoptosis in esophageal cancer cells through the demethylation and reactivation of the p16 gene." in: Oncology letters, Vol. 14, Issue 1, pp. 1152-1156, (2017) (PubMed).

Meng, Yang, Jack, Zhang, Moller, Spivey, Page, Tierney, Crowder: "Biochemical characterization and zinc binding group (ZBGs) inhibition studies on the catalytic domain of MMP7 (cdMMP7)." in: Journal of inorganic biochemistry, Vol. 165, pp. 7-17, (2016) (PubMed).

Wang, Li, Wu, Wu, Li, Yang, Chen, Xie, Huang, Du, Zhou: "miR-132 can inhibit glioma cells invasion and migration by target MMP16 in vitro." in: OncoTargets and therapy, Vol. 8, pp. 3211-8, (2015) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Lin, Wang, Jie, Hong, Li, Wang, Yu: "Inhibitory effects of miR-146b-5p on cell migration and invasion of pancreatic cancer by targeting MMP16." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 31, Issue 4, pp. 509-14, (2011) (PubMed).

Kurata, Maruyama, Kato, Sato, Yamamoto, Ozaki, Nitta, Nabeshima, Morita, Mizuno, Ito, Yuzawa, Matsuo: "Tissue-type plasminogen activator deficiency attenuates peritoneal fibrosis in mice." in: American journal of physiology. Renal physiology, Vol. 297, Issue 6, pp. F1510-7, (2009) (PubMed).

Jung, Römer, Keyszer, Lein, Kristiansen, Schnorr, Loening, Jung: "mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue." in: The Prostate, Vol. 55, Issue 2, pp. 89-98, (2003) (PubMed).

Synonyms and alternative names related to MMP16

matrix metallopeptidase 16 (Mmp16), matrix metallopeptidase 16 (MMP16), C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP, Mt3-mmp, Mt3mmp

Protein level used designations for MMP16

  • MMP-16
  • MT-MMP 3
  • MTMMP3
  • Membrane type 3-MMP
  • matrix metalloproteinase 16
  • matrix metalloproteinase-16
  • membrane-type matrix metalloproteinase 3
  • membrane-type-3 matrix metalloproteinase
  • MT3MMP
  • Putative transmembrane protein C8orf57
  • matrix metalloproteinase 16 (membrane-inserted)
  • membrane type-matrix metalloproteinase
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