Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN390146

Matrix Metallopeptidase 25 (MMP25) (C-Term), (AA 470-499) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms MMP20, MT6-MMP, Leukolysin, F730048C11Rik, MMP-25, MMP20A, MMPL1, MT-MMP 6, MT-MMP6, MT6MMP, MTMMP6
Epitope
»Alternatives C-Term, AA 470-499
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN390146
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen This MMP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-499 AA from the C-terminal region of human MMP25.
Clone RB2043
Isotype Ig
Specificity This MMP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MMP25.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MMP25
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP20 but has been renamed matrix metalloproteinase 25 (MMP25).
Molecular Weight 62554 DA
Gene ID 64386
UniProt NP_071913
Research Area Stem Cells, Protein Modifications, Cell Structure, Cancer
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Nagase, Woessner: "Matrix metalloproteinases." in: The Journal of biological chemistry, Vol. 274, Issue 31, pp. 21491-4, 1999 (PubMed).

Matsuda, Itoh, Koshikawa et al.: "Clusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36350-7, 2003 (PubMed).

Alternatives for antigen "Matrix Metallopeptidase 25 (MMP25)", type "Antibodies"
Hosts (19), (3)
Reactivities (22), (3)
Applications (21), (6), (6), (3), (2)
Epitopes (3), (1), (1), (1), (1)
Beacon