Alanine Glyoxylate Aminotransferase (AGXT) (AA 96-125), (Center) antibody

Details for Product No. ABIN390393
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Antigen
Synonyms AGT, SPT, Spat, PH1, AGT1, SPAT, TLH6, AGXT1, Agt1, Agxt1
Epitope
AA 96-125, Center
(3), (2), (1), (1)
Reactivity
Human
(18), (4), (1)
Host
Rabbit
(13), (5), (3)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(12), (6), (4), (2), (2), (1), (1)
Pubmed 2 references available
Catalog no. ABIN390393
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This AGXT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 AA from the Central region of human AGXT.
Clone RB18848
Isotype Ig
Specificity This AGXT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103~133 amino acids from the Center region of human AGXT.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name AGXT
Background AGXT is expressed only in the liver and protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification.
Synonyms: Serine--pyruvate aminotransferase, SPT, Alanine--glyoxylate aminotransferase, AGT, SPAT, AGT1, AGXT
Molecular Weight 43010 DA
Gene ID 189
UniProt P21549
Research Area Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Alanine Glyoxylate Aminotransferase (AGXT) (AA 96-125), (Center) antibody Western blot analysis of AGXT Antibody (Center) (ABIN390393) in HepG2 cell line lysates (35 µg/lane). AGXT (arrow) was detected using the purified polyclonal antibody.(8 µg/mL)
anti-Alanine Glyoxylate Aminotransferase (AGXT) (AA 96-125), (Center) antibody (2) AGXT Antibody (Center) (ABIN390393) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining
Background publications Bertoldi, Cellini, Paiardini et al.: "Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis." in: Biochimica et biophysica acta, Vol. 1784, Issue 9, pp. 1356-62, 2008 (PubMed).

Cellini, Montioli, Paiardini et al.: "Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation." in: The Journal of biological chemistry, Vol. 284, Issue 13, pp. 8349-58, 2009 (PubMed).

Hosts (13), (5), (3)
Reactivities (18), (4), (1)
Applications (12), (6), (4), (2), (2), (1), (1)
Epitopes (3), (2), (1), (1)
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