AGXT antibody
Quick Overview for AGXT antibody (ABIN7072987)
Target
See all AGXT AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Cross-Reactivity
- Human
-
Purification
- Affinity purification
-
Immunogen
- Recombinant protein corresponding to Mouse AGXT
-
-
-
-
Application Notes
- WB (M) 1:300-1:600, IHC/IF (H) 1:1000-1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
-
- AGXT (Alanine Glyoxylate Aminotransferase (AGXT))
-
Alternative Name
- AGXT
-
Background
- AGXT (AGT) is a key enzyme in glyoxylate detoxification. Mutations of AGXT lead to primary hyperoxaluria type I, a rare metabolic disease which is characterized by deficient AGXT, excessive hepatic oxalate production that leads to renal failure.
-
Molecular Weight
- 46 kDa
-
Gene ID
- 11611
-
UniProt
- O35423
-
Pathways
- Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport
Target
-