Early Growth Response 3 (EGR3) (AA 214-241), (Center) antibody

Details for Product No. ABIN390744
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Antigen
Synonyms zgc:92020, EGR-3, PILOT, Pilot
Epitope
AA 214-241, Center
(9), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(37), (21), (19), (14), (14), (13), (12)
Host
Rabbit
(36), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(23), (14), (10), (8), (7), (1), (1), (1)
Pubmed 2 references available
Quantity 400 μL
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Catalog No. ABIN390744
291.50 $
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Immunogen This EGR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-241 AA from the Central region of human EGR3.
Clone RB17955
Isotype Ig
Specificity This EGR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220~250 amino acids from the Center region of human EGR3.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EGR3
Background EGR3 is a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. This protein participates in the transcriptional regulation of genes in controling biological rhythm. It may also plays a role in muscle development.
Synonyms: Early growth response protein 3, EGR-3, Zinc finger protein pilot, PILOT, EGR3
Molecular Weight 42613 DA
Gene ID 1960
UniProt Q06889
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Early Growth Response 3 (EGR3) (AA 214-241), (Center) antibody Western blot analysis of EGR3 Antibody (Center) (ABIN390744) in mouse heart tissue lysates (35 µg/lane). EGR3 (arrow) was detected using the purified polyclonal antibody.
Product cited in: Hinze, Mayer, Harst et al.: "Adenosine A(3) receptor-induced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes." in: Journal of molecular and cellular cardiology, Vol. 53, Issue 5, pp. 639-45, 2012 (PubMed).

Background publications Yamada, Gerber, Iwayama et al.: "Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 8, pp. 2815-20, 2007 (PubMed).

Validation Images
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