ACVR2A antibody (N-Term)

Catalog No. ABIN391160

Product Details anti-ACVR2A Antibody

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Binding Specificity: AA 2-29, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVR2A antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, C, Rat, Sh

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ACVR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-29 amino acids from the N-terminal region of human ACVR2A.

Clone: RB08169-08170

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ACVR2A

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Alternative Name: ACVR2A (ACVR2A Products)

Synonyms: ACVR2 antibody, ACVR2A antibody, XSTK9 antibody, actrii antibody, acvr2 antibody, ACTRII antibody, Acvr2 antibody, rActR-II antibody, actr2a antibody, acvr2a antibody, wu:fa02e10 antibody, ActrIIa antibody, TactrII antibody, activin A receptor type 2A antibody, activin A receptor type 2A L homeolog antibody, activin A receptor type 2Aa antibody, activin receptor IIA antibody, ACVR2A antibody, acvr2a antibody, Acvr2a antibody, acvr2a.L antibody, acvr2aa antibody

Background: ACVR2A is an activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

Molecular Weight: 57848

Gene ID: 92

NCBI Accession: NP_001265508, NP_001265509, NP_001607

UniProt: P27037